Provide Acetyl Resveratrol - Chinaprice: contact company for price
Appearance: White to off-white powder
Test Method: HPLC
Molecular Formula: C20H18O6
Molecular Weight: 354.35
CAS No: 42206-94-0
Description: Acetyl-resveratrol is called prodrug on medicinal chemistry, it is more stable than trans-resveratrol. When absorbed, it returns to resveratrol under action of metabolism.
The main drawback with current resveratrol forms is the low oral bioavailability. Resveratrol is water-insoluble substance; it can be easily excreted when intaked. This is why finding these acetylated analogs has been so significant; they have better bioavailability and increased biological activity in comparison to the base phenolic compounds. Multiple studies have shown that acetylated analogs of Resveratrol exhibit the same or higher inhibitory effects on various tumor cell lines than Resveratrol itself while being absorbed faster and resisting cellular breakdown. Since the acetylated Resveratrol is being absorbed more quickly, plasma levels in the body reach a higher level and at a faster rate. Through ester hydrolysis enzymes in the body actually break down acetylated Resveratrol back to its natural phenolic form.
Dosage form varied from pill to capsule up to different requirements when use Acetyl-resveratrol as raw material.
Resveratrol is unstable because its Hydroxyls are active group when exposure to oxygen, light and heat. The purpose of acetylation is to inactivate Resveratrol before absorption.
Acetyl-resveratrol is soluble in water (but not resveratrol). Therefore, it can be widely used in cosmetic industry, pharmaceutics, food, beverage, health products.
- Posted By: Changsha Natural-ex Inc.
- Phone: 8673184681820610
- Address: FL17, Unit 2, Block 1, Xiangteng City Plaza, No.43, Changsha City, China
- Website: http://www.natural-ex.com
Published date: April 17, 2013 -
- Business Description: Natural ex Inc., located in the west side of Xiang River in Changsha, is a professional manufacturer of botanical extracts and natural effective ingredients. We own a team which dedicated to the R&D, production and marketing of botanical extract since 1990s, also have advanced equipment and facilities which are used for the production of botanical extracts. In the past years, we researched and developed several hundred of producing technology of botanical extract, now our total annual production capacity of herbal raw material is about 5,000mt and we can supply more than 800mt botanical extracts each year.
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