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  • Anti Active Gi Mouse Monoclonal Antibody - USA

    price: contact company for price

    Catalog Number: 26901

    Gene Symbol: Gnai

    Description: Anti-Active Gi Mouse Monoclonal Antibody

    Background: Heterotrimeric G proteins are critical cellular signal transducers. Gi represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gi proteins are being explored.

    Immunogen: Recombinant full length protein of active Gi1

    Applications: IP, IHC

    Recommended Dilutions: 1 µg for 1~2 mg total cellular proteins for IP;

    1:100 dilution for IHC

    Concentration: 1 mg/ml

    Host: mouse

    Format: Liquid

    Clonality: Monoclonal

    Isotype: IgG1

    Purity: Purified from ascites

    Storage buffer:

    Preservative: no

    Constituents: PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol

    Species Reactivity: Anti-active Gi antibody recognizes active Gi1, Gi2, and Gi3 of vertebrates.

    Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles


    Company Contact:


    • Phone: 6109452007

    • Address: 24 Whitewoods Lane, Malvern, PA, USA

    • Email: Email


    Published date: June 6, 2013 -

    • Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins). These unique antibodies do not recognize the inactive (GDP bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

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