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  • Anti Egfr G719s Mouse Monoclonal Antibody - USA

    price: contact company for price

    Catalog Number: 26083

    Gene Symbol: EGFR

    Description: Anti-EGFR(G719S) Mouse Monoclonal Antibody

    Background: EGFR is a receptor tyrosine kinase for ligands of the EGF family.

    EGFR activates several signaling cascades to convert extracellular cues into appropriate cellular responses.

    Defects in EGFR are associated with cancers such as lung cancer.

    Immunogen: A synthetic peptide from the internal region of human EGFR which includes the mutation of G719S.

    Applications: ELISA, WB, IHC, IF

    Recommended Dilutions:

    ELISA: 1: 1000-1: 5000

    WB: 1: 1000-1: 2000

    IHC: 1: 50-1: 1000

    IF: 1: 50-1: 100

    Concentration: 1 mg/ml

    Host: mouse

    Format: Liquid

    Clonality: Monoclonal

    Isotype: IgG

    Purity: Purified from ascites

    Storage buffer:

    Preservative: no

    Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

    Species Reactivity: Recognizes EGFR(G719S), but not wild type EGFR protein of vertebrates.

    Storage Conditions: Store at -20°C.

    Avoid freeze / thaw cycles.


    Company Contact:


    • Phone: 6109452007

    • Address: 24 Whitewoods Lane, Malvern , PA , USA

    • Email: Email


    Published date: June 6, 2013

    • Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins).

      These unique antibodies do not recognize the inactive (GDP bound) G proteins.

      These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections.

      Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

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