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  • Anti Pik3ca H1047r Rabbit Polyclonal Antibody - USA

    price: contact company for price

    Catalog Number: 21146

    Gene Symbol: PIK3CA(H1047R)

    Description: Anti-PIK3CA(H1047R) Rabbit Polyclonal Antibody

    Background: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit.

    The catalytic subunit is encoded by the PIK3CA gene.

    It phosphorylates PtdIns, PtdIns4P and PtdIns(4, 5)P2 - The PIK3CA gene is one of the most frequently mutated genes in human cancers.

    Immunogen: A synthetic peptide around the H1047R region of PIK3CA, human origin.

    Applications: ELISA, WB, IHC, IP

    Recommended Dilutions:

    ELISA: 1: 100-1: 5000

    WB: 1: 100-1: 1000

    IHC: 1: 10-1: 100

    Concentration: 0.1 mg/ml

    Host: Rabbit

    Format: Liquid

    Clonality: Polyclonal

    Isotype:

    Purity: Purified from serum

    Storage buffer:

    Preservative: no

    Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

    Species Reactivity: Anti-PIK3CA(H1047R) antibody recognizes PIK3CA(H1047R) of vertebrates.

    Storage Conditions: Store at -20°C.

    Avoid freeze / thaw cycles


    Company Contact:


    • Phone: 6109452007

    • Address: 24 Whitewoods Lane, Malvern , PA , USA

    • Email: Email


    Published date: June 6, 2013

    • Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins).

      These unique antibodies do not recognize the inactive (GDP bound) G proteins.

      These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections.

      Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

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