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  • Anti Ras Q61r Mouse Monoclonal Antibody - USA

    price: contact company for price

    Catalog Number: 26192

    Gene Symbol: RAS (Q61R)

    Description: Anti-Ras (Q61R) Mouse Monoclonal Antibody

    Background: Ras protein is a membrane associated GTPase signaling protein that regulates proliferation, differentiation, and cell survival.

    Ras Q61R mutation result in decreased GTPase activity and constitutive signaling, and is correlated with the development of pancreatic intraepithelial neoplasia and lung lesions.

    Immunogen: A synthetic peptide from the internal region of Ras which includes the mutation of Q61R, human origin.

    Applications: ELISA, WB, IHC

    Recommended Dilutions:

    ELISA 1: 100-1: 5000

    WB 1: 100-1: 1000

    IHC 1: 50-1: 100

    Concentration: 1 mg/ml

    Host: Mouse

    Format: Liquid

    Clonality: Monoclonal

    Isotype:

    Purity: Purified from ascites

    Storage buffer:

    Preservative: no

    Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

    Species Reactivity: Recognizes Ras (Q61R), but not wild type Ras protein from vertebrates.

    Storage Conditions: Store at -20°C.

    Avoid freeze / thaw cycles


    Company Contact:


    • Phone: 6109452007

    • Address: 24 Whitewoods Lane, Malvern , PA , USA

    • Email: Email


    Published date: June 6, 2013

    • Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins).

      These unique antibodies do not recognize the inactive (GDP bound) G proteins.

      These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections.

      Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

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