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  • Cd163 Antibody - China

    price: 299.00 Dollar US$

    Product Name: CD163 Antibody
    Code : CSB-RA801238A0HU
    Abbreviation : Scavenger receptor cysteine-rich type 1 protein M130
    Storage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
    Immunogen : A synthesized peptide
    Species Reactivity : Human
    Tested Applications : ELISA, IHC, FC; Recommended dilution: IHC:1:50-1:500
    Relevance : Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.
    Form : Liquid
    Conjugate : Non-conjugated
    Storage Buffer : Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Purification method : Affinity-chromatography
    Isotype : Rabbit IgG
    Clonality : Monoclonal
    Alias : Scavenger receptor cysteine-rich type 1 protein M130, Hemoglobin scavenger receptor, CD163, Soluble CD163, sCD163, CD163, M130
    Species : Human
    Research Area : Immunology


    Company Contact:


    • Phone: 862787582341

    • Address: Building B11, #818 Gaoxin Road, Wuhan, China

    • Email: Email


    Published date: December 20, 2017 -

    • Business Description: CUSABIO is a leading biotechnology company specialized in production of

      high quality products for gene, protein, antibody, ELISA kit, raw

      material for production of diagnostic kit, drug residues, food safety

      small molecules & other small molecules.

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