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Lysostaphin - China

price: contact company for price

Lysostaphin, an endopeptidase specific for the cell wall peptidoglycan

of staphylococcus, is an extremely potent antistaphylococcal agent. It’s

molecular weight is 27kDa and is comprised of 246 amino acids. The

isoeletric point of it is 10.5-11.0. The key enzymatic reaction of

lysostaphin is the specific cleavage of the Gly-Gly bond in the

pentaglycine subunit of the cell wall peptidoglycan and lyses cells in

all metabolic states. Lysostaphin also hydrolyzes glycine-rich proteins

such as insoluble elastin. .Both activities have a pH optimum in the

neutral range and are inhibited by agent that would chelate the

endogenous zinc, suggesting that zinc interferes directly with the

catalytic activity of the enzyme. Lysostaphin has been in animals and

topically in man against certain infections. It is used as a research

and diagnostic tool. Because it lyses staphylococcus efficiently, it is

widely used when preparing staphylococcal DNA or other cellular

components for genetic and biochemical studies and for the preparation

of protoplasts for transformation. Preparation and analysis of bacterial

DNA has become a powerful tool used by clinical and other

microbiologists in studies aimed at tracing source of infection or

bacterial contamination


Please see our contact information below

Company Contact:

  • Phone: 0086057188257817

  • Address: Room3A09, No.452,No.6 street, Hangzhou Economic-Te, Hangzhou, China

  • Email: Email

Published date: September 7, 2012 -

  • Business Description: involved in international trade import export of goods, products, and services

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