Recombinant Human Acetoacetyl Coa Synthetase His Tagged - Chinaprice: contact company for price
member 1, Protein sur-5 homolog, AACS, and ACSF1, is a member of the ATP-
dependent AMP-binding enzyme family. AACS is highly expressed in kidney,
heart and brain, but low in liver. AACS is an essential enzyme for the
synthesis of fatty acid and cholesterol from ketone bodies. AACS in
adipose tissue plays an important role in utilizing ketone body for the
fatty acid-synthesis during adipose tissue development. AACS was found
to be highly expressed in mouse adipose tissue, and GC box and C/EBPs
motif were crucial for AACS promoter activity. Moreover, AACS promoter
activity was controlled mainly by C/EBPalpha during adipogenesis. AACS
is a novel cytosolic ketone body (acetoacetate)-specific ligase, the
physiological role of which remains to be elucidated.
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Published date: June 28, 2013 -
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