Sell Recombinant Carboxypeptidase B Trypsin - Chinaprice: contact company for price
FOR MANUFACTURING OF RECOMBINANT HUMAN INSULIN
Animal Origin Free, No Virus Contaminant
ANIMAL ORIGIN FREE
In the past 20 years, there has been a shift away from using bovine- or porcine-derived insulin to recombinant human insulin. Recombinant human insulin is generally AOF level 1 component due to the usage of bovine- or porcine-derived trypsin and carboxypeptidase B in its manufacturing. However, as worries about animal origin contaminants have increased, many biopharmaceutical companies have begun to consider producing AOF level 2 or AOF level 3 insulin. YaxinBio offers recombinant trypsin and recombinant carboxypeptidase B as essential components for the AOF level 3 insulin production. The value addition and safety offered in this AOF level 3 version provides a tremendous advantage to insulin manufacturers to fetch better market price in already crowded and pricesensitive insulin market-place.
USE OF RECOMBINANT CARBOXYPEPTIDASE B AND RECOMBINANT TRYPSIN IN INSULIN MANUFACTURING
Figure 1. HPLC spectra of enzymatic digestion of human proinsuin. Panel A and B correspond to enzymatic digestion of human proinsulin to generatehuman insulin with porcine-derived carboxypeptidase B and trypsin, and recombinant carboxypeptidase B and recombinant trypsin from YaxinBio, respectively.
Source E. Coli
Physical form lyophilized powder
Special activity ≥170 units/mg pro for recombinant carboxypeptidase B;
≥ 3000 USP units/ mg pro for recombinant trypsin.
Purified by HPLC
Purity ≥ 95%
Foreign activity No chymotrypsin, carboxypeptidase A, and other protease contaminant.
One Unit of carboxypeptidase B activity hydrolyzes one micromole of hippuryl-L-arginine per
minute at 25℃, pH 7.65.
One USP unit of trypsin activity will produce a Delta A253 of 0.003 per minute in a reaction
volume of 3.0ml at pH7.6 at 25℃，with BAEE as a substrate (1cm light path).
Products Cat.No Special Activity Manufacturer
Carboxypeptidase B RCPB01170 ≥170u/mg pro YaxinBio
Porcine Trypsin RPT03030 ≥3000 USP u/mg pro YaxinBio
Sell Recombinant Carboxypeptidase b Trypsin
Please inquiry for your need now
- Posted By: China Shanghai Yaxin Biotechnology Co. Ltd
- Phone: 862154336592
- Address: Room 101, Building 1, No. 466 Yin Du Road, Xu Hui , shanghai, China
- Website: http://www.yaxinbio.com
Published date: November 16, 2012 -
- Business Description: involved in international trade import export of goods, products, and services
Sell Recombinant Carboxypeptidase BBiotech Supplies - China Shanghai Yaxin Biotechnology Co. Ltd - China - November 16, 2012 - contact company for price
Recombinant Carboxypeptidase B Animal Origin Free, No Virus Contaminant DESCRIPTIONS Carboxypeptidase B catalyzes hydrolysis of the basicamino acids lysine, arginine and histidine from the Cterminal of polypeptides. The molecular weight is 34, 500 da...
Sell Recombinant Human Trypsin 2Biotech Supplies - China Shanghai Yaxin Biotechnology Co. Ltd - China - November 16, 2012 - contact company for price
Recombinant Human Trypsin 2 Animal Origin Free, No Virus Contaminant DESCRIPTIONS Trypsin is a member of the serine protease family. Trypsin will cleave peptides on the C-terminal side of lysine and arginine amino acid residues. Recombinant human Try...
Sell Recombinant Porcine Trypsin 1Biotech Supplies - China Shanghai Yaxin Biotechnology Co. Ltd - China - November 16, 2012 - contact company for price
Recombinant Porcine Trypsin 1 Animal Origin Free, No Virus Contaminant DESCRIPTIONS Trypsin is a member of the serine protease family. Trypsin will cleave peptides on the C-terminal side of lysine and arginine amino acid residues. The pH optimum of t...
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