Anti Brca1 C61g Mouse Monoclonal Antibody - USAprice: contact company for price
Gene Symbol: BRCA1, BRCC1, IRIS, PNCA4, PPP1R53, PSCP
Description: Anti- BRCA1 ( C61G) Mouse Monoclonal Antibody
Background: BRCA1 is normally expressed in cells of breast and other tissues, where it helps repair damaged DNA or destroy cells if DNA cannot be repaired. It is involved in the repair of chromosomal damage with an important role in the error- free repair of DNA double- strand breaks. If BRCA1 itself is damaged by a BRCA1 mutation, damaged DNA is not repaired properly, and this increases the risk for breast cancer.
Immunogen: A synthetic peptide from the internal region of BRCA1 which includes the mutation of C61G, human origin.
Applications: ELISA, WB, IHC
ELISA: 1: 1000- 1: 2000
WB: 1: 500- 1: 1000
IHC: 1: 50- 1: 100
Concentration: 1 mg/ ml
Purity: Purified from ascites
Constituents: PBS ( without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Recognizes C61G mutant, but not wild- type BRCA1 of vertebrates.
Storage Conditions: Store at - 20°C. Avoid freeze / thaw cycles
- Posted By: NewEast Biosciences
- Phone: 6109452007
- Address: 24 Whitewoods Lane, Malvern, PA, USA
- Website: http://neweastbio.com
Published date: March 11, 2015 -
- Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins). These unique antibodies do not recognize the inactive (GDP bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.
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