48 visiting now: 15 China China flag 14 USA USA flag 10 France France flag 4 Russia Russia flag 2 Netherlands Netherlands flag 2 India India flag 1 Germany Germany flag

Anti Egfr L747 P753 S Mouse Monoclonal Antibody - USA

price: contact company for price

Catalog Number: 26287

Gene Symbol: EGFR/ HER1/ ERBB1

Description: Anti- EGFR ( L747- P753) S Mouse Monoclonal Antibody

Background: EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS- RAF- MEK- ERK, PI3 kinase- AKT, PLCgamma- PKC and STATs modules. Defects in EGFR are associated with lung cancer ( LNCR) .

Immunogen: A synthetic peptide from the internal region of EGFR which includes the mutation of ( L747- P753) S, human origin.

Applications: ELISA, WB, IF, IHC

Recommended Dilutions:

ELISA: 1: 1000- 1: 5000

WB: 1: 500- 1: 1000

IHC: 1: 50- 1: 100

Concentration: 1 mg/ ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal


Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS ( without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes EGFR ( L747- P753) S, but not wild type EGFR protein from vertebrates.

Storage Conditions: Store at - 20°C. Avoid freeze / thaw cycles

Company Contact:

  • Phone: 6109452007

  • Address: 24 Whitewoods Lane, Malvern, PA, USA

  • Email: Email

Published date: March 11, 2015 -

  • Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins). These unique antibodies do not recognize the inactive (GDP bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

Related listings

  • Cashew Nut Shell Liquid Best Quality
    Cashew Nut Shell Liquid Best Quality
    Chemical - Hoang Kim Nguyen Exim Co., Ltd - Vietnam - October 20, 2016 - 1.00 Dollar US$

    Dear Valued Customer, We, Hoang Kim Nguyen Exim Co., LTD are one of the leading suppliers, manufacturers and exporters of Biomass Products from Vietnam. Established in 2010, Hoang Kim Nguyen Exim Co., LTD has been greatly successful in making a mark ...

  • 90% Ammonium Sulfite Content
    90% Ammonium Sulfite Content
    Chemical - Shandong Tiantai steel-plastic Co.,Ltd - China - October 19, 2016 - check with company for price

    Ammonium sulfite is used in the pharmaceutical, food, chemical industry, papermaking, etc. In papermaking industry, it is mainly used for non-wood based pulping (such as straw) to break down lignin in plant fiber. Content:90% Appearance:White solid A...

  • 54% Ammonium Bisulfite Solution
    54% Ammonium Bisulfite Solution
    Chemical - Shandong Tiantai steel-plastic Co.,Ltd - China - October 18, 2016 - contact company for price

    Purity : 54% Appearance : Clear to light yellow, Free of particulates Odor : Light SO2 Density : @20degree Solubility in water : Soluble in all proportions Storage temperature : 20degree-26degree Item : FOB Qingdao Used for:water treatment;used for r...

Safe Trade Tips

  • Ask for business references and check them
  • Use a payment method that offers better protection for all such as Letters of credit and verified professional escrow services. Avoid payments in advance such as money transfers
  • Verify their business via their local Chamber of Commerce
  • Search the internet using their website address, their business name, their phone and fax numbers, and their email addresses to see if you can find any feedback about them.
  • Get to know more about scams to avoid: Internet Crime Complaint Center - International Financial Scams
  • This site is never involved in any transaction, and does not handle payments, shipping, guarantee transactions, provide escrow services, or offer "buyer protection" or "seller certification"