32 visiting now: 14 USA USA flag 10 China China flag 2 France France flag 2 Netherlands Netherlands flag 1 Korea Korea flag 1 Russia Russia flag 1 Singapore Singapore flag 1 Sweden Sweden flag

Highlighted Companies

Anti Egfr L747 P753 S Mouse Monoclonal Antibody - USA

price: contact company for price

Catalog Number: 26287

Gene Symbol: EGFR/ HER1/ ERBB1

Description: Anti- EGFR ( L747- P753) S Mouse Monoclonal Antibody

Background: EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS- RAF- MEK- ERK, PI3 kinase- AKT, PLCgamma- PKC and STATs modules. Defects in EGFR are associated with lung cancer ( LNCR) .

Immunogen: A synthetic peptide from the internal region of EGFR which includes the mutation of ( L747- P753) S, human origin.

Applications: ELISA, WB, IF, IHC

Recommended Dilutions:

ELISA: 1: 1000- 1: 5000

WB: 1: 500- 1: 1000

IHC: 1: 50- 1: 100

Concentration: 1 mg/ ml

Host: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype:

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS ( without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes EGFR ( L747- P753) S, but not wild type EGFR protein from vertebrates.

Storage Conditions: Store at - 20°C. Avoid freeze / thaw cycles


Company Contact:


  • Phone: 6109452007

  • Address: 24 Whitewoods Lane, Malvern, PA, USA

  • Email: Email


Published date: March 11, 2015 -

  • Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins). These unique antibodies do not recognize the inactive (GDP bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

Related listings



  • Lignin Cellulose Fiber
    Lignin Cellulose Fiber
    Chemical - Henan Huikang Industrial Co.,Ltd - China - January 14, 2017 - check with company for price

    Property: Suitable for improvement, optimizing the performance of building materials, new features and functions, building materials and conformance to enhance the stability of production and construction.Its technology is mainly used to thixotropic,...

  • Polycarboxylate Superplasticizer Pce
    Polycarboxylate Superplasticizer Pce
    Chemical - Henan Huikang Industrial Co.,Ltd - China - January 14, 2017 - check with company for price

    Polycarboxylate Superplasticizer is a kind of free–flowing powder form superplasticizer, as a universal product, designed for applications of flowing mortars with universal and special cementitious binders. Composed of polycarboxylate ether copolymer...

  • Redispersible Polymer Powder
    Redispersible Polymer Powder
    Chemical - Henan Huikang Industrial Co.,Ltd - China - January 14, 2017 - check with company for price

    Property: SP1126 dispersible emulsion powder for water soluble and disperse latex powder, chooses import of VAE emulsion spray drying, vinyl acetate - ethylene copolymer powder, polyvinyl alcohol as protective colloid.After dealing with spray drying....



Safe Trade Tips

  • Ask for business references and check them
  • Use a payment method that offers better protection for all such as Letters of credit and verified professional escrow services. Avoid payments in advance such as money transfers
  • Verify their business via their local Chamber of Commerce
  • Search the internet using their website address, their business name, their phone and fax numbers, and their email addresses to see if you can find any feedback about them.
  • Get to know more about scams to avoid: Internet Crime Complaint Center - International Financial Scams
  • This site is never involved in any transaction, and does not handle payments, shipping, guarantee transactions, provide escrow services, or offer "buyer protection" or "seller certification"