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Peptide Libraries Synthesis Custom - China

price: contact company for price

We offer Peptide Libraries by Mimotopes.

Peptide libraries are a powerful tool in biological research

for screening large numbers of peptides in the search for

the few, critical bioactive peptides.

Specialists of peptide library by Mimotopes could design

peptide library for free based on customer requirements and

experimental purposes, provide consultation and guidance of

peptide library design and other customized services in

connection with customer' s practical problems.

Mimotopes library ( PepsetTM) is synthesized on the original

patent of mimotopes ( SynPhase lantern) , it makes the

homogeneity and the stability of product' s quality

guaranteed. But also ensure the high efficiency of the

production, and ensure that customers could receive the

products in the shortest time.

The design tools below will guide you through the steps of

isolating minimum length active peptide sequences,

identifying critical amino acid residues, designing analogs

for sequence optimization and will provide indicative

pricing for all peptide sets.

Overlapping

Overlapping peptide libraries are ideal for T- cell epitope

searching, because T cell epitopes are by nature short

linear peptides from the primary protein sequence. They are

also appropriate for scanning the primary sequence of

proteins for linear, or " continuous" , B- cell ( antibody-

defined) epitopes.

Truncation

Truncation peptide libraries are used to identify the

shortest amino acid sequence needed for activity. The

library is constructed by systemically removing the flanking

residues of the original peptide. If the essential amino

acids are known ( eg. by Alanine Scanning) , the direction of

truncation can be tailored to maintain these residues,

whilst truncating the opposite end.

T- cell Truncated

Truncated peptide libraries allow the testing of all

possible T- cell epitopes ( ie. all 8 to 11- mers) across a

protein of interest. In each tube, we provide equimolar

mixtures of the four C- terminal peptides for each nominal

11- mer. After screening, positive tubes can be deconvoluted

for precise epitope identification.

Alanine Scan

Alanine Scanning is able to identify specific amino acid

residues responsible for a peptide' s activity. Alanine is

used to substitute each residue sequentially.

Substitution of an essential amino acid results in a

reduction in peptide activity, with the degree of activity

reduction taken as a relative measure of the importance of

the amino acid being substituted.

Positional Scan

Positional scanning is an important tool for peptide

sequence optimization. This identifies an amino acid of

interest at a single position and substitutes it with all

other natural amino acids one at a time. Increases in

activity will identify the preferred amino acid residues at

this positions.

Combinatorial 2- Positional Scan

sequence optimization. Two position combinatorial scanning

identifies amino acids of interest at two given positions

and substitutes them with all other natural amino acids one

at a time. Increases in activity will identify the preferred

amino acid residues at these positions.

Combinatorial 3- Positional Scan

sequence optimization. Three position combinatorial scanning

identifies amino acids of interest at three given positions

Scrambled

Scrambled libraries are constructed through permutation of

the original peptide sequence. They are typically used as:

1. Negative controls to show that a specific sequence rather

than the amino acid composition is critical for activity; or

2. A tool for finding new leads by creating a random

screening library.


Company Contact:


  • Phone: 8601082037209

  • Address: Rm.1310 Tower A Huayuan Building No.32 Huayuan Eas, beijing, China

  • Email: Email


Published date: April 30, 2014 -

  • Business Description: Beijing ZhogXingBoMai Co, Ltd. is a company ,which is specialized in

    producing, processing and marketing peptide products, biological

    laboratory equipment, healthcare equipment, microscopes and water

    purification system .We have a complete and scientific quality

    management system. The integrity, strength and product quality of

    Beijing Zhongxing Technology Co, Ltd. is recognized by the industry.

    Welcome to visit, guide and to negotiate business.

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