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3 4 Chlorbutyl 1h Indol 5 Carbonitril Cas 143612 79 7 - China

price: contact company for price

What is 3- ( 4- Chlorbutyl) - 1H- indol- 5- carbonitril?

3- ( 4- Chlorbutyl) - 1H- indol- 5- carbonitril is a key intermediate for preparation of Vilazodone, a dual- acting serotonergic antidepressant for managing major depression.

Application of 3- ( 4- Chlorbutyl) - 1H- indol- 5- carbonitril

3- ( 4- Chlorbutyl) - 1H- indol- 5- carbonitril is a key intermediate for synthetizing Vilazodone.

Vilazodone is developed by Clinical Data. Originally, its chemical compound was developed by the German company Merck KGaA. Vilazodone is a serotonergic antidepressant for treating major depressive disorder, and was approved by the FDA for use in the United States in 2011. It is produced by Trovis Pharmaceuticals LLC under the trade name Viibryd. There are 3 specifications of 10mg, 20mg, and 40mg with the Vilazodone tablet approved in the market.

Vilazodone hydrochloride is synthesized from 5- ( 1- Piperazinyl) benzofuran- 2- carboxamide and 3- ( 4- Chlorobutyl) - 1H- indole- 5- carbonitrile by condensation and salification.

Preparation of 3- ( 4- Chlorbutyl) - 1H- indol- 5- carbonitril

3- ( 4- Chlorbutyl) - 1H- indole- 5- carbonitrile is prepared from 5- cyanoindole and 4- chlorobutyl chloride by acylation and reduction.


Company Contact:


  • Phone: 862154795870

  • Address: Floor 29, CapitaMalls Plaza, No. 6088 Humin Rd., Shanghai, China

  • Email: Email


Published date: March 9, 2015 -

  • Business Description: Banff Green Technologies, Inc. is a technologically innovative company

    that focuses on chemicals, materials, pharmaceuticals, crop science and

    environmental technology. The company headquarter is based in Shanghai,

    China. Our research and development team is comprised of a talented and

    experienced team of PhD s with strong scientific backgrounds dedicated

    to our mission. We are also supported by strong infrastructure, which

    include state of the art lab facilities, two pilot facilities and seven

    manufacturing sites located in five provinces in China.

    Our core businesses span over the following areas: R & D, production and sales of fine and specialty chemicals, contract manufacturing services and custom synthesis.

    Our main products are: fluorinated fine chemicals (mainly Diethyl fluoromalonate and 5 fluorine pyrimidine derivatives), chiral compounds (amino acids and their derivatives, in particular D 2 Aminobutyric acid, L 2 Aminobutanamide hydrochloride, chloramphenicol and Valnemulin hydrochloride).

    Our corporate mission is to achieve environmental protection and sustainability while being socially responsible through our research and innovation. We sincerely hope to better serve our customers through every facets of their needs and together we can achieve a more sustainable future.

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