Medical Biodegradable Ploymer Poly Dl Lactide Co Glycolide - Chinaprice: contact company for price
Product Model: PDLG
Chemical Formula : (C6H8O4)m (C4H4O4)n
Instructions : Poly(DL-lactide-co-glycolide) (PDLGA) is
produced from lactic acid and glycolic acid. It is non-toxic
and has excellent biodegradability, biocompatibility, film
or capsule forming ability. PDLGA is widely used in
pharmaceutical, medical engineering materials and modern
industrial fields. In the United States, PDLGA has been
approved by the FDA and is formally included in the United
States pharmacopoeia as pharmaceutical materials.
PDLGA is a amorphous polymer. The glass transition
temperature (Tg) of PLGA is 40 - 60 °C. It has been widely
used in medical surgical sutures, anti-adhesion membrane,
tissue engineering scaffolds and so on. The degradation rate
of PDLGA increases with the increase of GA proportion.
Different types of PDLGA can be produced using
differentmonomer ratio . For example, PDLLGA 75:25 indicates
that the polymer consists of 75% DL-lactic acid and 25%
The degradation products of PDLGA are lactic
acid and glycolic acid, so they do not have toxic side
effects when used as the pharmaceutical and biological
materials. PDLGA has been widely used in biomedical fields,
such as medical anti-adhesion membrane, skin graft, stitched
wound, injectable microcapsules, microspheres, implants,
scaffolds for tissue engineering.
Appearance : White or pale yellow particles
DL-lactide/Glycolic mol/mol : 85/15, 75/25, 50/50
IV (Intrinsic viscosity) : 0.2-1.8 dL/g
Specific Rotation ( ，chloroform): -10 - +10°
Glass Transition Temperature: 48-53°C
Melting Point : Amorphous
Residual Monomers : <1%
Residual Solvents: < 0.05%
Extractable Heavy Metals: < 10 ppm
Stannum (Catalyst): < 200 ppm
Density: 1.24 g/cm3
Sulfate Ash: < 0.05%
Model Ratio DL-LA/GA IV DL-LA/GA Proportional Range
PDLG85-03 85/15 0.3 82/18-88/12 0.20-0.40
PDLG85-05 85/15 0.5 82/18-88/12 0.40-0.70
PDLG85-08 85/15 0.8 82/18-88/12 0.70-1.00
PDLG85-12 85/15 1.2 82/18-88/12 1.00-1.40
PDLG85-16 85/15 1.6 82/18-88/12 1.40-1.80
PDLG85-20 85/15 2.0 82/18-88/12 >1.80
PDLG75-03 75/25 0.3 72/28-78/22 0.20-0.40
PDLG75-05 75/25 0.5 72/28-78/22 0.40-0.70
PDLG75-08 75/25 0.8 72/28-78/22 0.70-1.00
PDLG75-12 75/25 1.2 72/28-78/22 1.00-1.40
PDLG75-16 75/25 1.6 72/28-78/22 1.40-1.80
PDLG75-20 75/25 2.0 72/28-78/22 >1.80
PDLG50-03 50/50 0.3 47/53-53/47 0.20-0.40
PDLG50-05 50/50 0.5 47/53-53/47 0.40-0.70
PDLG50-08 50/50 0.8 47/53-53/47 0.70-1.00
PDLG50-12 50/50 1.2 47/53-53/47 1.00-1.40
PDLG50-16 50/50 1.6 47/53-53/47 1.40-1.80
PDLG50-20 50/50 2.0 47/53-53/47 >1.80
- Posted By: Changchun Sinobiomaterials Co.,Ltd.
- Phone: 15848782739
- Address: No. 666A Chaoqun Street, High-tech Industrial Deve, JILIN, China
- Website: http://www.sinobiom.com
Published date: April 7, 2013 -
- Business Description: Changchun SinoBiomaterials Co., Ltd was founded in April 2007, High Tech
Enterprises. It is mainly engaged in the manufacture of biodegradable
polymer materials for medical applications, as well as the development
and industrialization of the downstream products, such as L lactide (L
LA), glycolic acid (GA), poly(L lactic acid) (PLLA), poly(glycolic acid)
(PGA), poly(ε caprolactone) (PCL), monomethoxyl poly(ethylene glycol) b
poly(lactic acid)(mPEG PLA) , Poly(D,L lactide) (PDLLA) and their
copolymers, as well as absorbable internal fixation devices for fracture
including bone screws and bone plates, tissue engineering scaffolds for
bone repair, materials for sustained drug delivery, etc.
Our company occupies an area of 10,000 meter square with a total investment of 33.55 million yuan. There are an integrated experimental building and a production workshop in accordance with GMP standards, both occupying 3,500 meter square. Over 90% of the employees in our company hold college degrees. The main management staffs have studied aboard for years. They have profound scientific attainments and abundant experience of management. With their expertise in chemical, biological and medical fields, our main technical staffs have strong capability for innovation and development of relative products.
Changchun SinoBiomaterials Co., Ltd is technically supported by Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences. The Science and Technology Innovation Centre for poly(lactic acid) based biodegradable materials of Jilin Province and the Science and Technology Innovation Centre for poly(lactic acid) based biomaterials of Changchun City were founded jointly by SinoBiom and CIAC in 2007 and 2009, respectively. The foundation of these two research centres has been promoting the application of Medical biodegradable polymer materials in the medicine field and continuing to promote the pace of industrialization, with the goal of achieving the integration of production and studying and research.
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