Product Name Rat Protein Kinase B Pkb Akt Elisa Kit - Chinaprice: check with company for price
Product Type : ELISA Kit
Code : CSB-E12655r
Abbreviation : AKT1
Protein Biological Process 1 : Apoptosis/Autophagy
Alias : AKT, MGC99656, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, AKT1 kinase|RAC-alpha serine/threonine-protein kinase|protein kinase B|rac protein kinase alpha
Species : Rat
Protein Biological Process 3 : Apoptosis
Sample Types : serum, plasma, cell culture supernates, tissue homogenates
Research Area : Signal Transduction
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Target details : The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.
- Posted By: Cusabio Biotech Co., Ltd
- Phone: 862787582341
- Address: Building B11, #818 Gaoxin Road, Wuhan, China
- Website: http://www.cusabio.com/
Published date: June 15, 2016 -
- Business Description: CUSABIO is a leading biotechnology company specialized in production of
high quality products for gene, protein, antibody, ELISA kit, raw
material for production of diagnostic kit, drug residues, food safety
small molecules & other small molecules.
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