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Polypeptides Powder Dsip - China

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DSIP ( Delta sleep- inducing peptide)

Delta sleep- inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.

Its aminoacid sequence is Т rр - А lа - Gly- Gly- Asp- Ala- Ser- Gly- Glu. However, it is the only neuropeptide in history whose gene is unknown, raising serious questions regarding the actual existence of this peptide in nature.

DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif: N- Trp- Ala- Gly- Gly- Asp- Ala- Ser- Gly- Glu- C

It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body . In the pituitary it co- localises with many peptide and non- peptide mediators such as corticotropin- like intermediate peptide ( CLIP) , adrenocorticotrophic hormone ( ACTH) , melanocyte- stimulating hormone ( MSH) , thyroid- stimulating hormone ( TSH) and melanin concentrating hormone ( MCH) . It is abundant in the gut secretory cells and in the pancreas where it co- localises with glucagon.

In the brain its action may be mediated by NMDA. In another study Delta sleep- inducing peptide stimulated Acetyltransferase activity through α 1 receptors in rats. It is unknown where DSIP is synthesized.

In vitro it has been found to have a low molecular stability with a half life of only 15 minutes due to the action of a specific aminopeptidase- like . It has been suggested that in the body it complexes with carrier proteins to prevent degradation, or exists as a component of a large precursor molecule, but as yet no structure or gene has been found for this precursor.

Evidence supports the current belief that it is regulated by glucocorticoids.


Company Contact:


  • Phone: 8618188938018

  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou, China

  • Email: Email

Published date: September 4, 2014 -

  • Business Description: Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. was founded in 2013, a branch of "Yuancheng" Group, which is located in Tianyuan District, Zhuzhou City The Economic Centre of Changsha Zhuzhou and Xiangtan Cities Group. It is a large high tech chemical enterprise which specialized in fine chemicals , flavors and fragrances, food additives, pharmaceutical raw material and intermediates. Companies affiliated factory has advanced production equipment and plants, perfect quality assurance and control system, whole set of High Pressure Liquid Chromatography/Gas Chromatography/UV Spectrophotometer to conduct effective product analysis and monitoring. Company factory has passed ISO9001 quality system certification and international KOSHER certification.

    Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. based in chemical industry, lead by food chemical market. Complete e commerce networks make guarantee for timely service to the world customers. To meet the needs of customers, each product is elite, which is recommended and selected by professional and experienced technicals for customers. The company has independent import and export rights, products exported to foreign markets with high quality and good service, established good business relationship with other countries in Europe, America, Asia, etc. All the staffs will make unremitting efforts to strive for outstanding quality, make excellent brand and service the market by first class products.

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