Anti Alk D1225n Mouse Monoclonal Antibody - USAprice: contact company for price
Gene Symbol: ALK, CD246, NBLST3
Description: Anti- ALK ( D1225N) Mouse Monoclonal Antibody
Background: Anaplastic lymphoma kinase ( ALK) also known as CD246 ( cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in cancers.
Immunogen: A synthetic peptide from the internal region of ALK which includes the mutation of D1225N, human origin.
Applications: ELISA, WB
ELISA: 1: 1000- 1: 5000
WB: 1: 500- 1: 2000
Concentration: 1 mg/ ml
Purity: Purified from ascites
Constituents: PBS ( without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Recognizes D1225N mutant, but not wild- type ALK of vertebrates.
Storage Conditions: Store at - 20Â°C. Avoid freeze / thaw cycles
- Posted By: NewEast Biosciences
- Phone: 6109452007
- Address: 24 Whitewoods Lane, Malvern, PA, USA
- Website: http://neweastbio.com
Published date: May 4, 2016 -
- Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins). These unique antibodies do not recognize the inactive (GDP bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.
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