Anti Sumo 1 Rabbit Polyclonal Antibody - USAprice: contact company for price
Gene Symbol: SUMO1
Description: Anti- SUMO- 1 Rabbit polyclonal Antibody
Background: Small Ubiquitin- like Modifier or SUMO proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMOylation is a post- translational modification involved in various cellular processes, such as nuclear- cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle. There are 3 confirmed SUMO isoforms in humans: SUMO- 1, SUMO- 2 and SUMO- 3. SUMO- 2 and - 3 show a high degree of similarity to each other and are distinct from SUMO- 1.
Immunogen: A synthetic peptide corresponding to residues near the C- terminal of human SUMO- 1.
Applications: ELISA, WB, IHC, IP
ELISA: 1: 1000- 1: 5000
WB: 1: 100- 1: 1000
IHC: 1: 50- 1: 100
Concentration: 1 mg/ ml
Purity: Purified from serum
Constituents: PBS ( without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Detects SUMO- 1 but not SUMO- 2/ 3 from vertebrates.
Storage Conditions: Store at - 20°C. Avoid freeze / thaw cycles
- Posted By: NewEast Biosciences
- Phone: 6109452007
- Address: 24 Whitewoods Lane, Malvern, PA, USA
- Website: http://neweastbio.com
Published date: April 14, 2015 -
- Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins). These unique antibodies do not recognize the inactive (GDP bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.
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