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  • Anti Fgfr1 V664l Mouse Monoclonal Antibody - USA

    price: contact company for price

    Catalog Number: 26259

    Gene Symbol: FGFR1, BFGFR, CD331, CEK, FGFBR, FLG

    Description: Anti- FGFR1 ( V664L) Mouse Monoclonal Antibody

    Background: The protein FGFR1 is highly conserved between members and throughout evolution. This particular family member of FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations of FGFR1 protein have been associated with Pfeiffer syndrome, Jackson- Weiss syndrome, Antley- Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome.

    Immunogen: A synthetic peptide from the internal region of FGFR1 which includes the mutation of V664L, human origin.

    Applications: ELISA, WB, IHC

    Recommended Dilutions:

    ELISA: 1: 1000- 1: 2000

    WB: 1: 500- 1: 1000

    IHC: 1: 50- 1: 100

    Concentration: 1 mg/ ml

    Host: Mouse

    Format: Liquid

    Clonality: Monoclonal

    Isotype:

    Purity: Purified from ascites

    Storage buffer:

    Preservative: no

    Constituents: PBS ( without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol

    Species Reactivity: Recognizes V664L mutant, but not wild- type FGFR1 of vertebrates.

    Storage Conditions: Store at - 20°C. Avoid freeze / thaw cycles


    Company Contact:


    • Phone: 6109452007

    • Address: 24 Whitewoods Lane, Malvern, PA, USA

    • Email: Email


    Published date: March 11, 2015 -

    • Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins). These unique antibodies do not recognize the inactive (GDP bound) G proteins. These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections. Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

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