Peptide Libraries Synthesis Custom - Chinaprice: contact company for price
Peptide libraries are a powerful tool in biological research
for screening large numbers of peptides in the search for
the few, critical bioactive peptides.
Specialists of peptide library by Mimotopes could design
peptide library for free based on customer requirements and
experimental purposes, provide consultation and guidance of
peptide library design and other customized services in
connection with customer' s practical problems.
Mimotopes library ( PepsetTM) is synthesized on the original
patent of mimotopes ( SynPhase lantern) , it makes the
homogeneity and the stability of product' s quality
guaranteed. But also ensure the high efficiency of the
production, and ensure that customers could receive the
products in the shortest time.
The design tools below will guide you through the steps of
isolating minimum length active peptide sequences,
identifying critical amino acid residues, designing analogs
for sequence optimization and will provide indicative
pricing for all peptide sets.
Overlapping peptide libraries are ideal for T- cell epitope
searching, because T cell epitopes are by nature short
linear peptides from the primary protein sequence. They are
also appropriate for scanning the primary sequence of
proteins for linear, or " continuous" , B- cell ( antibody-
Truncation peptide libraries are used to identify the
shortest amino acid sequence needed for activity. The
library is constructed by systemically removing the flanking
residues of the original peptide. If the essential amino
acids are known ( eg. by Alanine Scanning) , the direction of
truncation can be tailored to maintain these residues,
whilst truncating the opposite end.
T- cell Truncated
Truncated peptide libraries allow the testing of all
possible T- cell epitopes ( ie. all 8 to 11- mers) across a
protein of interest. In each tube, we provide equimolar
mixtures of the four C- terminal peptides for each nominal
11- mer. After screening, positive tubes can be deconvoluted
for precise epitope identification.
Alanine Scanning is able to identify specific amino acid
residues responsible for a peptide' s activity. Alanine is
used to substitute each residue sequentially.
Substitution of an essential amino acid results in a
reduction in peptide activity, with the degree of activity
reduction taken as a relative measure of the importance of
the amino acid being substituted.
Positional scanning is an important tool for peptide
sequence optimization. This identifies an amino acid of
interest at a single position and substitutes it with all
other natural amino acids one at a time. Increases in
activity will identify the preferred amino acid residues at
Combinatorial 2- Positional Scan
sequence optimization. Two position combinatorial scanning
identifies amino acids of interest at two given positions
and substitutes them with all other natural amino acids one
at a time. Increases in activity will identify the preferred
amino acid residues at these positions.
Combinatorial 3- Positional Scan
sequence optimization. Three position combinatorial scanning
identifies amino acids of interest at three given positions
Scrambled libraries are constructed through permutation of
the original peptide sequence. They are typically used as:
1. Negative controls to show that a specific sequence rather
than the amino acid composition is critical for activity; or
2. A tool for finding new leads by creating a random
- Posted By: Beijing ZhogXingBoMai Co, Ltd.
- Phone: 8601082037209
- Address: Rm.1310 Tower A Huayuan Building No.32 Huayuan Eas, beijing, China
- Website: http://biomedi.com.cn
Published date: April 30, 2014 -
- Business Description: Beijing ZhogXingBoMai Co, Ltd. is a company ,which is specialized in
producing, processing and marketing peptide products, biological
laboratory equipment, healthcare equipment, microscopes and water
purification system .We have a complete and scientific quality
management system. The integrity, strength and product quality of
Beijing Zhongxing Technology Co, Ltd. is recognized by the industry.
Welcome to visit, guide and to negotiate business.
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