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  • Synphase Lanterns A Modular Solid Phase Platform As An Alternative To Resin - China

    price: contact company for price

    SynPhase Lanterns - a modular solid phase platform as an

    alternative to resins

    Characteristics of Ideal Solid Phase

    1. Equivalent Reactivity of Functional Groups

    approach solution phase conditions

    2. Physicochemical Compatibility

    with compounds being synthesized

    with polar and non- polar solvents

    3. Good Mechanical Properties

    under wide range of solvent, temperature and pressures

    Why Solid Phase Synthesis?

    1. Simplifies parallel handling

    2. Readily automated

    3. Drive reactions to completion with excess reagent

    4. Remove excess: reagents and

    5. by- products by washing

    Morphology of Solid Supports

    Microporous gels

    low cross- linked copolymers such as polystyrene ( PS) ,

    polyamides ( PA) , etc.

    Macroporous or macroreticular resins

    controlled- pore glass or highly cross- linked polystyrene.

    Pellicular supports

    composed of two layers

    mobile accessible surface on a solid core material

    eg. glass, PTFE ( Polytetrafluoroethene) , PP( polypropylene) or

    highly cross- linked PS


    Launched March 2000

    Adopted as library synthesis platform by several big

    pharmaceutical companies

    Polystyrene or Polyamide surface on polypropylene

    Quantised solid phase

    Can be used as Matrix Format or Direct sort format

    Structure of Lantern Surface

    Uniform 50 micron graft

    High loading

    Excellent kinetics

    Temperature stability

    ( - 80& deg; C to 100& deg; C )

    Minimal swelling

    Stable to agitation

    SynPhaseTM technology used in Parallel mode

    Lanterns ( in white) fixed to stems ( in blue) which are fixed

    to stem holder in 8x12 array format ( 96) . This can now go

    into 96 well plate each having different reaction mixtures.

    The Classic MultiPinTM Method

    Simple handling

    Convenient 8x12 array format

    Detachable stems

    Ideal for washes and simultaneous cleavage

    Any chemistry carried out on Resins is transferable to

    Lanterns with minimum modification

    Synthesis of peptide VQAAIDYING on Rink Lanterns using a CEM


    Solution A 1.46 g HBTU in 10 mL DMF

    Solution B 0.8 g HOBT in 10 mL DMF

    Coupling solution

    AA Production solution 0.82 mL

    Solution A 0.64 mL

    Solution B 0.64 mL

    NMM 0.064 mL

    Fundamental differences between SynPhase& trade; Lanterns and


    Handling convenience

    Rapid and uniform kinetics

    Rapid washing

    Broad applications

    solid phase synthesis

    parallel synthesis, tagged based techniques

    solution phase synthesis

    scavengers, catch and release, support bound reagents

    Cost effective

    Company Contact:

    • Phone: 8601082037209

    • Address: Rm.1310 Tower A Huayuan Building No.32 Huayuan Eas, beijing, China

    • Email: Email

    Published date: April 30, 2014 -

    • Business Description: Beijing ZhogXingBoMai Co, Ltd. is a company , which is specialized in

      producing, processing and marketing peptide products, biological

      laboratory equipment, healthcare equipment, microscopes and water

      purification system .We have a complete and scientific quality

      management system. The integrity, strength and product quality of

      Beijing Zhongxing Technology Co, Ltd. is recognized by the industry.

      Welcome to visit, guide and to negotiate business.

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