Rifampicin Capsule 300mg - Chinaprice: 2.90 Dollar US$
It is bactericidal against a wide range of micro-organisms and interferes with their synthesis of nucleic acids by inhibiting DNA-dependent RNA polymerase.It has the ability to kill intracellular or the spectrum of activity ganisms.The spectrum of actioity including Mycobacterium tuberculosis and M.leprea staphylococci.Neisseria meningitidis, N.gonorrhoeae, Legionella spp., Rifampicin Chlamydia trachomatis and some anaerobic bacteria.At high conc entrations it is active against some viruses.MICs for the most sensitive organisms(chlamydia, staphylococci)tend to range from about 0.01 to 0.02 ug per ml.While the MIC for most susc eptible mycobacteria ranges from 0.1 to 2 ug per ml.
Rifampicin is readily absorbed from the gastro intestinal tract and peak plasma concentrations of about 7 to 10 ug per ml have been reported 2 to 4 hours after a dose of 600 mg but there may be considerable interindvidual variation.Approximately 80% wouldbound to plasma proteins.It is widely distributed in body tissues and fluids and diffures into the cerebrospinal fluid when the meninges are inflamed an can crosses the placenta and distrbute in breast milk.Half-lives for rifampicin have been reported to range initially from 2 to 5 hours.It is rapidly metabolised in the liver and excreted in the bile.Meanwhile up to 30% may be excreted in the urine.
Rifampicin in used , notably is combination with isoniazid and pyrazinamide, as a component of multidrug regimens for the treatmrnt of tuberculosis, and with dapsone and clofazimine in the treatment of leprosy.Other uses include treatment of staphylococcal infections, brucellosis, and legionnaires disease and the prophylaxis of haemophilus and meningococcal meningitis.
Rifampicin is usually well tolerated.The main adverse effects are a flu-like syndrome and a cutaneous syndrome.Hepatotoxicity also occurs.Gastor-intestinal adverse effects include nausea, vomiting, anorexia, diarrhoea, and epigastric distress.
Liver function should be checked before and during treatment.Blood counts should be monitored during prolonged treatment and in patients with hepatic disorders.
The usual adults dose of rifampicin is 600 mg daily by mouth.preferably on an empty stomach orally administration on an ermpty stomach in single daily doses of 10 mg per kg body-weight(maximum 600 mg)to children and adults is recommended.The maximum dose is considered to be 900 mg.
Store in airtight containers protect from light in cool place.
Validity: Three Years
Inner Packing: 300mg 10*10/box
- Posted By: Anhui Medipharm Co., Ltd
- Phone: +8618955123129
- Address: No.288, Huaining Road, Shushan District,Hefei City, Anhui, China, Hefei, Anhui Province, China
- Website: http://www.ahmedipharm.com
Published date: May 26, 2016 -
- Business Description: Anhui Medipharm Co., Ltd. is a professional supplier for medicine and pharmaceutical products in China. We have focused on manufacturing and distributing western finished medicines, medical consumables, diagnosis equipments, surgical dressing products over 10 years, accumulated a wealth of experience. Our products have been exported to more than 40 countries, mainly in Asia, Africa, Middle East, South America and Europe, just like Cambodia, Philippines, Vietnam, Afghanistan, Pakistan, Turkey, Nigeria, Liberia, Congo, Somali,Guinea, Chile, Gambia, France and so on.
To supply sustainable, high quality products, competitive price and satisfactory service is our mission. We won high recognition in the international market by professional product knowledge, efficient supply chain management and excellent service, establishing extensive and mature distribution channels in international market.
Professionalism, honesty and integrity are our cultures. We will try our best to offer good quality products with competitive prices and fast delivery for our customers. We are looking forward to setting up long-term cooperation relationship with you.
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