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  • Pharmacokinetic In Vitro Assays - China

    price: 1.00 Dollar US$

    Our pharmacokinetics department offers the clients a broad spectrum of high quality of services in the areas of in vitro ADME, in vivo pharmacokinetics and bioanalysis services, ranging from small molecules to large molecules, such as protein and antibody. The animal species involved in our services are non-human primate, canine, mice, rat, rabbit and hamster. Meanwhile, non-human primate experimental platform and isotope platform for protein/antibody are certified by the Shanghai Government.

    Available studies include:

    Method development and validation (GLP & Non-GLP)
    Pharmacokinetics (Tumor bearing rodents, Bioavailability, Crossover studies, Cassette (N in 1) dosing and analysis, effects of gender on pharmacokinetics, BBB penetration )
    Stability in vehicles and plasma
    Drug interaction studies
    In vitro metabolic stability
    Prediction and identification of major metabolites
    Toxicokinetics analysis
    Distribution studies

    Pharmacokinetics Package for IND Filing

    DMPK package for CFDA and FDA IND filing

    Chemical Compounds
    Traditional Chinese Medicine

    Metabolic Stability Services

    CYP Reaction Phenotyping
    Microsomal Stability
    S9 Stability
    Hepatocyte Stability
    Plasma Stability
    Metabolite Profiling & Identification

    Drug-Drug Interaction Services

    Cytochrome P450 and UGT Reaction Phenotyping
    Hepatocyte Induction
    Cytochrome P450 Inhibition
    Time Dependent Inhibition (Single Point)

    Permeability and Transporter Services

    Caco-2 Permeability
    P-gp Inhibition

    Available reaction phenotyping services include:

    Phase I:
    Cytochrome P450 Enzymes (CYP)

    Phase II:
    UDP-glucuronyltransferases (UGT)

    Metabolic Stability

    Microsomes stability
    Hepatocytes stability
    Plasma stability
    S9 stability

    Protein Binding Services

    Plasma Protein Binding
    Brain Tissue Binding
    Whole Blood Binding
    Blood to Plasma Ratio

    Company Contact:

    • Phone: +862158591500

    • Address: 585 Chuanda Road,Pudong,Shanghai201299,China, Shanghai, Pudong New Area, China

    • Email: Email

    Published date: September 1, 2016 -

    • Business Description: Medicilon offers fully integrated pharmaceutical services for the global scientific community. We focus on providing an exceptional client-centered experience and advancing the drug discovery process.

      Since the founding of our company in 2004, our integrated services across biology, chemistry and preclinical services are uniquely designed to help clients developing their research and discovery programs from the initial idea stage to the IND filing phase.

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