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Pharmacokinetic In Vitro Assays - China

price: 1.00 Dollar US$

Our pharmacokinetics department offers the clients a broad spectrum of high quality of services in the areas of in vitro ADME, in vivo pharmacokinetics and bioanalysis services, ranging from small molecules to large molecules, such as protein and antibody. The animal species involved in our services are non-human primate, canine, mice, rat, rabbit and hamster. Meanwhile, non-human primate experimental platform and isotope platform for protein/antibody are certified by the Shanghai Government.

Available studies include:

Method development and validation (GLP & Non-GLP)
Pharmacokinetics (Tumor bearing rodents, Bioavailability, Crossover studies, Cassette (N in 1) dosing and analysis, effects of gender on pharmacokinetics, BBB penetration )
Stability in vehicles and plasma
Drug interaction studies
In vitro metabolic stability
Prediction and identification of major metabolites
Toxicokinetics analysis
Distribution studies

Pharmacokinetics Package for IND Filing

DMPK package for CFDA and FDA IND filing

Chemical Compounds
Traditional Chinese Medicine

Metabolic Stability Services

CYP Reaction Phenotyping
Microsomal Stability
S9 Stability
Hepatocyte Stability
Plasma Stability
Metabolite Profiling & Identification

Drug-Drug Interaction Services

Cytochrome P450 and UGT Reaction Phenotyping
Hepatocyte Induction
Cytochrome P450 Inhibition
Time Dependent Inhibition (Single Point)

Permeability and Transporter Services

Caco-2 Permeability
P-gp Inhibition

Available reaction phenotyping services include:

Phase I:
Cytochrome P450 Enzymes (CYP)

Phase II:
UDP-glucuronyltransferases (UGT)

Metabolic Stability

Microsomes stability
Hepatocytes stability
Plasma stability
S9 stability

Protein Binding Services

Plasma Protein Binding
Brain Tissue Binding
Whole Blood Binding
Blood to Plasma Ratio

Company Contact:

  • Phone: +862158591500

  • Address: 585 Chuanda Road,Pudong,Shanghai201299,China, Shanghai, Pudong New Area, China

  • Email: Email

Published date: September 1, 2016 -

  • Business Description: Medicilon offers fully integrated pharmaceutical services for the global scientific community. We focus on providing an exceptional client-centered experience and advancing the drug discovery process.

    Since the founding of our company in 2004, our integrated services across biology, chemistry and preclinical services are uniquely designed to help clients developing their research and discovery programs from the initial idea stage to the IND filing phase.

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