62 visiting now: 25 France France flag 15 USA USA flag 14 China China flag 2 Vietnam Vietnam flag 1 Netherlands Netherlands flag 1 Denmark Denmark flag 1 Germany Germany flag 1 Ireland Ireland flag 1 Canada Canada flag 1 Japan Japan flag

Highlighted Companies

  • Suzhou Rico Machinery Co., Ltd (China): RICO, a professional CNC machinery company, who integrated research, development and... http://www.ricocnc.com
  • A Hay & Grain Co Inc (USA): involved in international trade import export. At Anderson Hay we offer a wide variety of feed... http://www.anderson-hay.com/


  • Aprotinin Usp Bp Ip Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Aprotinin CAS No:

    Batch No: APR/ 011114 A. R. No 14/ FP/ APR/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies A white powder or Pallide- flavens powder

    2. PH 6.0 5.0 to 7.0

    3. Identification Complies Complies

    4. Clarity of solution Complies Complies

    5. Absorption 277 nm

    0.7 Have the largest absorption at λ =277nm not more than 0.8

    6. Water content 5.42%

    NMT 6.0%

    7. Protein of higher molecular mass 1.7% NMT 3.0%

    8. Pyrogen Complies

    Complies

    9. Abnormal toxity Complies Complies

    10. Depressor substance Complies Complies

    11. Valeance 3.48EPU/ mg not less than 3.0EPU/ mg on dry basis

    . .

    protinin

    Aprotinin. png

    Systematic ( IUPAC) name

    Aprotinin

    Clinical data

    AHFS/ Drugs. com monograph

    Pregnancy

    category

    X

    Legal status

    UK: Prescription- only ( POM)

    RX/ POM

    Dependence

    liability None

    Routes of

    administration Intravenous

    Pharmacokinetic data

    Bioavailability 100% ( intravenous)

    Identifiers

    CAS Registry Number 9087- 70- 1 Yes 9004- 04- 0

    ATC code B02AB01

    IUPHAR/ BPS 6570

    DrugBank DB06692 Yes

    UNII 04XPW8C0FL Yes

    KEGG D02971 Yes

    ChEMBL CHEMBL1201619

    Synonyms Trasylol, bovine pancreatic trypsin inhibitor

    Chemical data

    Formula C284H432N84O79S7

    Molecular mass 6511.51 g/ mol

    ( what is this? ) ( verify)

    The drug aprotinin ( Trasylol, previously Bayer and now Nordic Group pharmaceuticals) , is the small protein bovine pancreatic trypsin inhibitor ( BPTI) , an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. Under the trade name Trasylol, aprotinin was used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. Its main effect is the slowing down of fibrinolysis, the process that leads to the breakdown of blood clots. The aim in its use was to decrease the need for blood transfusions during surgery, as well as end- organ damage due to hypotension ( low blood pressure) as a result of marked blood loss. The drug was temporarily withdrawn worldwide in 2007 after studies suggested that its use increased the risk of complications or death; [ 1] this was confirmed by follow- up studies. Trasylol sales were suspended in May 2008, except for very restricted research use. In February 2012 the European Medicines Agency ( EMA) scientific committee reverted its previous standpoint regarding aprotinin, and has recommended that the suspension be lifted. [ 2] Nordic became distributor of aprotinin in 2012. [ 3]

    Contents [ hide]

    1 Chemistry

    2 Mechanism of drug action

    3 Drug efficacy

    4 Drug safety

    5 In vitro use

    6 History

    7 Current findings

    8 References

    9 External links

    Chemistry[ edit]

    BPTI seq ribbon sticks. jpg

    BPTI sequence, with its folded 3D structure represented by a ribbon for the secondary structure and a stick model ( gray) for the backbone and sidechains.

    Organism Bos taurus ( domestic cow)

    Symbol PTI

    Entrez 404172

    PDB 4PTI More structures

    RefSeq ( mRNA) NM_ 001001554

    RefSeq ( Prot) NP_ 001001554

    UniProt P00974


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 5, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

    Related listings



    • Bacampicillin Ip Bp Ep Usp Api Manufacturer
      Bacampicillin Ip Bp Ep Usp Api Manufacturer
      Pharmaceutical Drugs - SWAPNROOP DRUGS AND PHARMACEUTICALS - India - September 5, 2015 - contact company for price

      CERTIFICATE OF ANALYSIS Product Name Bacampicillin HydrochlorideUSP CAS No: 37661- 08- 8 Batch No: BAC/ 030313 A. R. No 13/ FP/ BAC/ 0303 Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13 Batch Quantity 165 kg Date of Retest Jan- 2016 Sr. No ...

    • Bacitracin Ip Bp Epusp Api Manufacturer
      Bacitracin Ip Bp Epusp Api Manufacturer
      Pharmaceutical Drugs - SWAPNROOP DRUGS AND PHARMACEUTICALS - India - September 5, 2015 - contact company for price

      CERTIFICATE OF ANALYSIS Product Name Bacitracin USP CAS No: 1405- 87- 4 Batch No: BAC/ 030313 A. R. No 13/ FP/ BAC/ 0303 Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13 Batch Quantity 165 kg Date of Retest Jan- 2016 Sr. No Test Results Acce...

    • Amyl Nitrite Usp Ip Bp Ep Manufacturer
      Amyl Nitrite Usp Ip Bp Ep Manufacturer
      Pharmaceutical Drugs - SWAPNROOP DRUGS AND PHARMACEUTICALS - India - September 5, 2015 - contact company for price

      CERTIFICATE OF ANALYSIS Product Name Amyl Nitrite USP CAS No: 110- 46- 3 Batch No: AMY/ 030313 A. R. No 13/ FP/ AMY/ 0303 Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13 Batch Quantity 165 kg Date of Retest Jan- 2016 Sr. No Test Results Acc...



    Safe Trade Tips

    • Ask for business references and check them
    • Use a payment method that offers better protection for all such as Letters of credit and verified professional escrow services. Avoid payments in advance such as money transfers
    • Verify their business via their local Chamber of Commerce
    • Search the internet using their website address, their business name, their phone and fax numbers, and their email addresses to see if you can find any feedback about them.
    • Get to know more about scams to avoid: Internet Crime Complaint Center - International Financial Scams
    • This site is never involved in any transaction, and does not handle payments, shipping, guarantee transactions, provide escrow services, or offer "buyer protection" or "seller certification"