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  • Bumetanide Usp Ip Ep Bp Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Bumetanide CAS No: 28395- 03- 1

    Batch No: BUM/ 011114 A. R. No 14/ FP/ BUM/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies White or almost white, crystalline powder

    2. Solubility Complies Practically insoluble in water, soluble in acetone and in alcohol, slightly soluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.

    3. Melting point 232.8ºC to 233.7ºC About 233 ℃

    4. Identification Complies Infrared absorption spectrphotometry

    5. Appearance of solution Complies The solution is clear and colourless

    6. Related substances

    Impurity A

    Impurity B

    Impurity C

    Impurity D

    Other impurity

    Total impurities

    0.001%

    Not detected

    0.03%

    0.07%

    NMT 0.1%

    NMT 0.2%

    7. Loss on drying 0.11% NMT 0.5%

    8. Sulfated ash Complies NMT 0.1%

    9. Assay 99.5% 99.0% to 101.0%

    .

    Bumetanide

    Bumetanide structure. svg

    Bumetanide ball- and- stick. png

    Systematic ( IUPAC) name

    3- butylamino- 4- phenoxy- 5- sulfamoyl- benzoic acid

    Clinical data

    Trade names Bumex

    AHFS/ Drugs. com monograph

    MedlinePlus a684051

    Pregnancy

    category

    AU: B3

    US: C ( Risk not ruled out)

    Legal status

    AU: Prescription Only ( S4)

    UK: Prescription- only ( POM)

    US: ℞ - only

    Routes of

    administration oral, intravenous, intramuscular

    Pharmacokinetic data

    Bioavailability almost complete ( ~80% )

    Protein binding 97%

    Metabolism hepatic

    Biological half- life ~0.8 hours

    Excretion renal

    Identifiers

    CAS Registry Number 28395- 03- 1 Yes

    ATC code C03CA02

    PubChem CID: 2471

    IUPHAR/ BPS 4837

    DrugBank DB00887 Yes

    ChemSpider 2377 Yes

    UNII 0Y2S3XUQ5H Yes

    KEGG D00247 Yes

    ChEBI CHEBI: 3213 Yes

    ChEMBL CHEMBL1072 Yes

    Chemical data

    Formula C17H20N2O5S

    Molecular mass 364.417 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 5, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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