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  • Candesartan Cilexetil Usp Ip Bp Ep Manufaturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Candesartan cilexetil CAS No:

    Batch No: CAN/ 011114 A. R. No 14/ FP/ CAN/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance complies White to off white crystal powder

    2. Identification Complies IR: similar to standard

    UV: similar to standard max at 255±2nm

    3 Solubility Complies Very soluble in chloroform.

    Slightly soluble in methanol.

    Insoluble in water.

    4. Loss On Drying 0.11% NMT 1.50%

    5. Melting point 161.7℃ to 163.5℃ 160℃ to 166℃

    6. Residue On Ignition 0.03% NMT 0.1%

    7. Heavy metals Complies NMT 20 PPM

    8. Particle size Complies 80% NLT 125u

    9. Total Microbial Count Complies NMT 100 cfu/ gm

    10. Enterabacteriaceae Complies NMT 10 cfu/ gm

    11. Fungal count Complies NMT 10 cfu/ gm

    12. 1 gm is free from Complies Staph aureus

    13. 10 gm Complies E. coli

    14. Ps. aeruginosa Complies Negative

    15. Salmonella spp Complies Negative

    16. Related Impurities

    Total impurities

    Candesartan

    Ethyleste candesartan

    Desethyl candesartan cilexetil

    Triphenyl methanol

    Any other unknown impurity

    0.2%

    0.05%

    0.03%

    0.06%

    0.03%

    NMT 0.2%

    NMT 0.1%

    17. Assay 99.80% 98.0% to 102.0%

    .

    Candesartan. svg

    Systematic ( IUPAC) name

    2- ethoxy- 1- ( { 4- [ 2- ( 2H- 1, 2, 3, 4- tetrazol- 5- yl) phenyl] phenyl} methyl) - 1H- 1, 3- benzodiazole- 7- carboxylic acid

    Clinical data

    Trade names Atacand

    AHFS/ Drugs. com monograph

    MedlinePlus a601033

    Pregnancy

    category

    AU: D

    Legal status

    ℞ ( Prescription only)

    Routes of

    administration oral

    Pharmacokinetic data

    Bioavailability 15% ( candesartan cilexetil)

    Metabolism Candesartan cilexetil: intestinal wall; candesartan: hepatic ( CYP2C9)

    Biological half- life 9 hours

    Excretion Renal 33% , faecal 67%

    Identifiers

    CAS Registry Number 139481- 59- 7 Yes

    ATC code C09CA06

    PubChem CID: 2541

    IUPHAR/ BPS 587

    DrugBank DB00796 Yes

    ChemSpider 2445 Yes

    UNII S8Q36MD2XX Yes

    KEGG D00626

    ChEBI CHEBI: 3347 Yes

    ChEMBL CHEMBL1016 Yes

    Chemical data

    Formula C24H20N6O3

    Molecular mass 440.45 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 5, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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