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Chlorotetracyclin Hydrochloride Usp Ip Bp Ep Manufacturer - India

price: contact company for price

CERTIFICATE OF ANALYSIS

Product Name Chlorotetracyclin hydrochloride CAS No:

Batch No: CHL/ 011114 A. R. No 14/ FP/ CHL/ 0111

Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

Batch Quantity 100 kg Date of Retest Jan- 2017

Sr. No Test Results Acceptance Criteria

1. Appearance Complies yellow powder

2. Identification

A

B

C

D

Complies

Complies

thin- layer chromatography

of discription of EP7.8

reaction of chlorides

HPLC

3. PH 2.47 2.3 to 3.3

4. Specific optical rotation - 244° - 235° to - 250°

5. Asbsorbance 0.216 NMT 4.0

6. Heavy metals Complies NMT 50 PPM

7. Water 0.45% NMT 2.0%

8. Sulphated ash 0.120% NMT 0.5%

9. Related substances

Impurity A

Impurity B

Impurity E

Impurity J

Impurity D

Impurity G

Impurity H

Impurity L

Impurity K

Unspeficied impurities

Sum of impurities other than A

1.63%

0.26%

0.39%

0.09%

0.06%

Not detected

0.15%

1.41%

NMT 4.0%

NMT 1.0%

NMT 0.3%

NMT 0.2%

NMT 0.15%

NMT 0.1%

NMT 2.0%

10. Assay

CTC HCL( anhydrous substance)

TC HCL( anhydrous substance)

CTC HCL+TC HCL( anhydroussubstance)

91.88%

4.3%

96.18%

NMT 89.5%

NMT 6.0%

94.5% to 102.0%

. .

Chlortetracycline

Chlortetracycline. svg

Chlortetracycline- 3D- balls. png

Systematic ( IUPAC) name

( 4S, 4aS, 5aS, 6S, 12aS, Z) - 2- [ amino( hydroxy) methylene] - 7- chloro- 4- ( dimethylamino) - 6, 10, 11, 12a- tetrahydroxy- 6- methyl- 4a, 5, 5a, 6- tetrahydrotetracene- 1, 3, 12( 2H, 4H, 12aH) - trione

Clinical data

AHFS/ Drugs. com Micromedex Detailed Consumer Information

Routes of

administration Oral, IV, topical

Pharmacokinetic data

Bioavailability 30%

Protein binding 50 to 55%

Metabolism Hepatic ( 75% )

Biological half- life 5.6 to 9 hours

Excretion Renal and biliary

Identifiers

CAS Registry Number 57- 62- 5 Yes

ATC code A01AB21 D06AA02 J01AA03 S01AA02 QG51AA08 QJ51AA03

ChemSpider 10469370 Yes

UNII WCK1KIQ23Q Yes

KEGG D07689 Yes

ChEMBL CHEMBL456066

Chemical data

Formula C22H23ClN2O8

Molecular mass 478.88 g/ mol


Company Contact:


  • Phone: 912406641875

  • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

  • Email: Email


Published date: September 6, 2015 -

  • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

    Pharmaceuticals of global quality standards to Pharma Companies all over

    the world. In our warehouse facilities, approved by FDA. we supply

    Pharmaceutical Finished products, Dental products and Active

    Pharmaceutical Ingredients.

    We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

    We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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