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  • Chlorotetracyclin Hydrochloride Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Chlorotetracyclin hydrochloride CAS No:

    Batch No: CHL/ 011114 A. R. No 14/ FP/ CHL/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies yellow powder

    2. Identification

    A

    B

    C

    D

    Complies

    Complies

    thin- layer chromatography

    of discription of EP7.8

    reaction of chlorides

    HPLC

    3. PH 2.47 2.3 to 3.3

    4. Specific optical rotation - 244° - 235° to - 250°

    5. Asbsorbance 0.216 NMT 4.0

    6. Heavy metals Complies NMT 50 PPM

    7. Water 0.45% NMT 2.0%

    8. Sulphated ash 0.120% NMT 0.5%

    9. Related substances

    Impurity A

    Impurity B

    Impurity E

    Impurity J

    Impurity D

    Impurity G

    Impurity H

    Impurity L

    Impurity K

    Unspeficied impurities

    Sum of impurities other than A

    1.63%

    0.26%

    0.39%

    0.09%

    0.06%

    Not detected

    0.15%

    1.41%

    NMT 4.0%

    NMT 1.0%

    NMT 0.3%

    NMT 0.2%

    NMT 0.15%

    NMT 0.1%

    NMT 2.0%

    10. Assay

    CTC HCL( anhydrous substance)

    TC HCL( anhydrous substance)

    CTC HCL+TC HCL( anhydroussubstance)

    91.88%

    4.3%

    96.18%

    NMT 89.5%

    NMT 6.0%

    94.5% to 102.0%

    . .

    Chlortetracycline

    Chlortetracycline. svg

    Chlortetracycline- 3D- balls. png

    Systematic ( IUPAC) name

    ( 4S, 4aS, 5aS, 6S, 12aS, Z) - 2- [ amino( hydroxy) methylene] - 7- chloro- 4- ( dimethylamino) - 6, 10, 11, 12a- tetrahydroxy- 6- methyl- 4a, 5, 5a, 6- tetrahydrotetracene- 1, 3, 12( 2H, 4H, 12aH) - trione

    Clinical data

    AHFS/ Drugs. com Micromedex Detailed Consumer Information

    Routes of

    administration Oral, IV, topical

    Pharmacokinetic data

    Bioavailability 30%

    Protein binding 50 to 55%

    Metabolism Hepatic ( 75% )

    Biological half- life 5.6 to 9 hours

    Excretion Renal and biliary

    Identifiers

    CAS Registry Number 57- 62- 5 Yes

    ATC code A01AB21 D06AA02 J01AA03 S01AA02 QG51AA08 QJ51AA03

    ChemSpider 10469370 Yes

    UNII WCK1KIQ23Q Yes

    KEGG D07689 Yes

    ChEMBL CHEMBL456066

    Chemical data

    Formula C22H23ClN2O8

    Molecular mass 478.88 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 6, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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