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  • Crizotinib Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Crizotinib CAS No: 877399- 52- 5

    Batch No: CRI/ 011114 A. R. No 14/ FP/ CRI/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies White solid

    2. Purity 99.6% NLT 99%

    3. e. e 99.9% NLT 99%

    Crizotinib

    Crizotinib2DACS. svg

    Systematic ( IUPAC) name

    3- [ ( 1R) - 1- ( 2, 6- dichloro- 3- fluorophenyl) ethoxy] - 5- ( 1- piperidin- 4- ylpyrazol- 4- yl) pyridin- 2- amine

    Clinical data

    Trade names Xalkori

    MedlinePlus a612018

    Licence data EMA: Link, US FDA: link

    Pregnancy

    category

    AU: D

    US: D ( Evidence of risk)

    Legal status

    AU: Prescription Only ( S4)

    CA: ℞ - only

    UK: Prescription- only ( POM)

    US: ℞ - only

    Routes of

    administration Oral

    Pharmacokinetic data

    Bioavailability 43%

    Protein binding 91%

    Metabolism Hepatic ( CYP3A4/ CYP3A5- mediated)

    Biological half- life 42 hours

    Excretion Faeces ( 63% ) , urine ( 22% )

    Identifiers

    CAS Registry Number 877399- 52- 5

    ATC code L01XE16

    PubChem CID: 11626560

    IUPHAR/ BPS 4903

    DrugBank DB08700 Yes

    ChemSpider 9801307 Yes

    UNII 53AH36668S Yes

    KEGG D09731

    ChEBI CHEBI: 64310

    ChEMBL CHEMBL601719 Yes

    Synonyms PF- 02341066

    1066

    PDB ligand ID VGH ( PDBe, RCSB PDB)

    Chemical data

    Formula C21H22Cl2FN5O

    Molecular mass 450.337 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 7, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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