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Crizotinib Usp Ip Bp Ep Manufacturer - India

price: contact company for price

CERTIFICATE OF ANALYSIS

Product Name Crizotinib CAS No: 877399- 52- 5

Batch No: CRI/ 011114 A. R. No 14/ FP/ CRI/ 0111

Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

Batch Quantity 100 kg Date of Retest Jan- 2017

Sr. No Test Results Acceptance Criteria

1. Appearance Complies White solid

2. Purity 99.6% NLT 99%

3. e. e 99.9% NLT 99%

Crizotinib

Crizotinib2DACS. svg

Systematic ( IUPAC) name

3- [ ( 1R) - 1- ( 2, 6- dichloro- 3- fluorophenyl) ethoxy] - 5- ( 1- piperidin- 4- ylpyrazol- 4- yl) pyridin- 2- amine

Clinical data

Trade names Xalkori

MedlinePlus a612018

Licence data EMA: Link, US FDA: link

Pregnancy

category

AU: D

US: D ( Evidence of risk)

Legal status

AU: Prescription Only ( S4)

CA: ℞ - only

UK: Prescription- only ( POM)

US: ℞ - only

Routes of

administration Oral

Pharmacokinetic data

Bioavailability 43%

Protein binding 91%

Metabolism Hepatic ( CYP3A4/ CYP3A5- mediated)

Biological half- life 42 hours

Excretion Faeces ( 63% ) , urine ( 22% )

Identifiers

CAS Registry Number 877399- 52- 5

ATC code L01XE16

PubChem CID: 11626560

IUPHAR/ BPS 4903

DrugBank DB08700 Yes

ChemSpider 9801307 Yes

UNII 53AH36668S Yes

KEGG D09731

ChEBI CHEBI: 64310

ChEMBL CHEMBL601719 Yes

Synonyms PF- 02341066

1066

PDB ligand ID VGH ( PDBe, RCSB PDB)

Chemical data

Formula C21H22Cl2FN5O

Molecular mass 450.337 g/ mol


Company Contact:


  • Phone: 912406641875

  • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

  • Email: Email


Published date: September 7, 2015 -

  • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

    Pharmaceuticals of global quality standards to Pharma Companies all over

    the world. In our warehouse facilities, approved by FDA. we supply

    Pharmaceutical Finished products, Dental products and Active

    Pharmaceutical Ingredients.

    We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

    We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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