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  • Diclofenac Diethylamine Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Diclofenac diethylamine CAS No:

    Batch No: DIC/ 011114 A. R. No 14/ FP/ DIC/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies White or slightly yellowish crystalline

    powder, slightly hygroscopic

    2. Identification Complies

    Complies IR- Spectrum

    TLC chromatogram

    3. PH 7.3 6.4 to 8.4

    4. APPEARANCE OF

    SOLUTION Complies

    0.020% CLEAR

    Absorption at 440nm max 0.05

    5. Heavy metals Complies NMT 10 PPM

    6. Single substance 0.48% NMT 1.0%

    7. Related substances

    Single impurity

    Total impurities

    Complies

    Complies

    NMT 0.2%

    NMT 0.5%

    8. Sulphated substances Complies NMT 0.1%

    9. Loss on drying 0.05% NMT 0.5%

    10. Assay 99.43% 99.0% to 101.0%

    . .

    Diclofenac

    Diclofenac. svg

    Clinical data

    Trade names Aclonac, Cataflam, Voltaren

    AHFS/ Drugs. com monograph

    MedlinePlus a689002

    Pregnancy

    category

    AU: C

    US: C ( Risk not ruled out) in 1st and 2nd trimester, D in 3rd trimester

    Legal status

    AU: Pharmacy Only ( S2) – S4

    UK: Prescription- only ( POM) ( P for topical formulation)

    ℞ - only in most preparations/ countries, limited OTC in some countries, manufacture and veterinary use is banned in India, Nepal, and Pakistan due to imminent extinction of local vultures

    Routes of

    administration oral, rectal, intramuscular, intravenous ( renal- and gallstones) , topical

    Pharmacokinetic data

    Protein binding More than 99%

    Metabolism hepatic, no active metabolites exist

    Biological half- life 1.2- 2 hr ( 35% of the drug enters enterohepatic recirculation)

    Excretion 40% biliary 60% urine

    Identifiers

    CAS Registry Number 15307- 86- 5 Yes

    ATC code D11AX18 M01AB05, M02AA15, S01BC03

    PubChem CID: 3033

    IUPHAR/ BPS 2714

    DrugBank DB00586

    ChemSpider 2925 Yes

    UNII 144O8QL0L1 Yes

    KEGG D07816 Yes

    ChEBI CHEBI: 47381 Yes

    ChEMBL CHEMBL139 Yes

    PDB ligand ID DIF ( PDBe, RCSB PDB)

    Chemical data

    Formula C14H11Cl2NO2

    Molecular mass 296.148 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 7, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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