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  • Etoposide Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Etoposide USP CAS No: 33419- 42- 0

    Batch No: ETO/ 030313 A. R. No 13/ FP/ ETO/ 0303

    Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

    Batch Quantity 165 kg Date of Retest Jan- 2016

    Sr. No Test Results Acceptance Criteria

    1. Appearance

    2. Solubility

    3. Identification

    Complies a) By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.

    Complies b) By HPLC: Retention time of the principle peak in the chromatogram obtained with sample solution should match with that of the principle peak in chromatogram obtained with standard solution.

    4. Related Substances

    Individual Impurity Total Impurity

    0.22 %

    1.45%

    NMT 0.5%

    NMT 2.0%

    5. Specific Optical Rotation at 20 0 C ( Anhydrous Basis) - 114º Between - 110° to - 118°

    6. Heavy Metals Complies 20ppm

    7. Water Content by KF 3.25% NMT 6.0%

    8. Residue On Ignition 0.03% NMT 0.1%

    9. Assay HPLC 97.6% 95.0% –105.0%

    . .

    Etoposide

    Etoposide. svg

    Etoposide ball- and- stick. png

    Systematic ( IUPAC) name

    4' - Demethyl- epipodophyllotoxin 9- [ 4, 6- O- ( R) - ethylidene- beta- D- glucopyranoside] , 4' - ( dihydrogen phosphate)

    Clinical data

    Trade names Etopophos

    AHFS/ Drugs. com monograph

    MedlinePlus a684055

    Pregnancy

    category

    AU: D

    US: D ( Evidence of risk)

    Legal status

    UK: Prescription- only ( POM)

    US: ℞ - only

    Routes of

    administration Oral, intravenous

    Pharmacokinetic data

    Bioavailability Highly variable, 25 to 75%

    Protein binding 97%

    Metabolism Hepatic ( CYP3A4 involved)

    Biological half- life Oral: 6 h. , IV: 6- 12 h. , IV in children: 3 h.

    Excretion Renal and fecal

    Identifiers

    CAS Registry Number 33419- 42- 0 Yes

    ATC code L01CB01

    PubChem CID: 36462

    IUPHAR/ BPS 6815

    DrugBank DB00773 Yes

    ChemSpider 33510 Yes

    UNII 6PLQ3CP4P3 Yes

    KEGG D00125 Yes

    ChEBI CHEBI: 4911 Yes

    ChEMBL CHEMBL44657 Yes

    Synonyms VP- 16; VP- 16- 213

    Chemical data

    Formula C29H32O13

    Molecular mass 588.557 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 8, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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