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  • Flupirtine Maleate Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Flupirtine Maleate CAS No:

    Batch No: FLU/ 011114 A. R. No 14/ FP/ FLU/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies White or off- white crystal powder

    2. Solubility Complies Soluble in methanol, insoluble in ether

    3. Melting point 186.5ºC to 186.9℃ 185ºC to 188℃

    4. Loss on drying 0.28% NMT 0.5%

    5. Impurity

    Single impurity

    0.13%

    NMT 0.2%

    6. Assay 99.7% NLT 99.0%

    Flupirtine

    Flupirtine. svg

    Flupirtine3Dan. gif

    Systematic ( IUPAC) name

    ethyl { 2- amino- 6- [ ( 4- fluorobenzyl) amino] pyridin- 3- yl} carbamate

    Clinical data

    AHFS/ Drugs. com International Drug Names

    Pharmacokinetic data

    Bioavailability 90% ( oral) , 70% ( rectal) [ 1]

    Metabolism Hepatic to 2- amino- 3- acetylamino- 6- ( para- fluorobenzylamino) pyridine ( which has 20- 30% the analgesic potential of its parent compound) , para- fluorohippuric acid[ 2] and a mercapturic acid metabolite, presumably formed from a glutathione adduct[ 3]

    Biological half- life 6.5 hrs ( average) , 11.2- 16.8 hrs ( average 14 hrs) ( elderly) , 8.7- 10.9 hrs ( average 9.8 hrs) ( in those with moderate- level renal impairment) [ 1]

    Excretion 72% of flupirtine and its metabolites appear in urine and 18% appear in feces[ 4]

    Identifiers

    CAS Registry Number 56995- 20- 1

    ATC code N02BG07

    PubChem CID: 53276

    IUPHAR/ BPS 2598

    ChemSpider 48119

    UNII MOH3ET196H Yes

    KEGG D07978 Yes

    ChEMBL CHEMBL255044

    Chemical data

    Formula C15H17FN4O2

    Molecular mass 304.32 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 8, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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