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Fluticasone Propionate Usp Ip Bp Ep Manufacturer - India

price: contact company for price

CERTIFICATE OF ANALYSIS

Product Name Fluticasone Propionate CAS No: 80474- 14- 2

Batch No: FLU/ 011114 A. R. No 14/ FP/ FLU/ 0111

Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

Batch Quantity 100 kg Date of Retest Jan- 2017

Sr. No Test Results Acceptance Criteria

1. Appearance Complies White to off white crystalline powder

2. Identification Complies Spectrum

3. Melting point 272.1ºC to 272.6ºC 272ºC to 273ºC

4. Heavy metals Complies NMT 20 PPM

5. Total impurities 1.67% NMT 2.0%

6. Loss on drying 0.31% NMT 1.0%

7. Assay by HPLC 98.62% 97% to 102%

Fluticasone propionate

Fluticasone propionate. svg

Systematic ( IUPAC) name

S- ( fluoromethyl) - 6α , 9- difluoro- 11β , 17- dihydroxy- 16α - methyl- 3- oxoandrosta- 1, 4- diene- 17β - carbothioate, 17- propanoate

Clinical data

AHFS/ Drugs. com monograph

Pregnancy

category

US: C ( Risk not ruled out)

C for Intranasal and Inhaled

Legal status

UK: Pharmacy medicines

US: OTC

Routes of

administration Intranasal, Inhaled, Topical Cream or Ointment

Pharmacokinetic data

Bioavailability 0.51% ( Intranasal)

Protein binding 91%

Metabolism Intranasal

Hepatic ( CYP3A4- mediated)

Biological half- life 10 hours

Excretion Renal

Identifiers

CAS Registry Number 80474- 14- 2 Yes

ATC code D07AC17 & D07AC04 ( topical)

PubChem CID: 444036

IUPHAR/ BPS 7080

DrugBank DB00588 Yes

ChemSpider 392059 Yes

UNII O2GMZ0LF5W Yes

ChEBI CHEBI: 31441 Yes

ChEMBL CHEMBL1473 Yes

Chemical data

Formula C25H31F3O5S

Molecular mass 500.57 g/ mol

SMILES


Company Contact:


  • Phone: 912406641875

  • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

  • Email: Email


Published date: September 8, 2015 -

  • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

    Pharmaceuticals of global quality standards to Pharma Companies all over

    the world. In our warehouse facilities, approved by FDA. we supply

    Pharmaceutical Finished products, Dental products and Active

    Pharmaceutical Ingredients.

    We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

    We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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