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  • Hydrochlorothiazide Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name HYDROCHLOROTHIAZIDE CAS No:

    Batch No: HYD/ 011114 A. R. No 14/ FP/ HYD/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies White to off- white crystalline powder.

    2. Identification Complies

    Complies IR

    UV

    3. Solubility Complies Very slightly soluble in water, soluble in

    acetone, sparingly soluble in ethanol ( 96 per

    cent) . It dissolves in dilute solutions of alkali

    hydroxides.

    4. Chloride Complies NMT 0.035%

    5. Selenium Complies NMT 0.003%

    6. Related substances

    Any peak

    Sum of peak

    0.03%

    0.09%

    NMT 0.5%

    NMT 0.9%

    7. Heavy metals Complies NMT 0.001%

    8. Residue on ignition 0.09% NMT 0.1%

    9. 4- Amino- 6- chloro- 1.3-

    - Benzenedisulfonamide 0.35% NMT 1%

    10. Loss on drying 0.21% NMT 0.5%

    11. Organic volatile impurities Complies Meets the requirements

    12. Assay 99.39% 98% to 102%

    Hydrochlorothiazide

    Hydrochlorothiazide- 2D- skeletal. png

    Hydrochlorothiazide- from- xtal- 3D- balls. png

    Systematic ( IUPAC) name

    6- chloro- 1, 1- dioxo- 3, 4- dihydro- 2H- 1, 2, 4- benzothiadiazine- 7- sulfonamide

    Clinical data

    Trade names Apo- hydro, Aquazide h, Dichlotride among others, Oretic

    AHFS/ Drugs. com monograph

    MedlinePlus a682571

    Pregnancy

    category

    B ( D if used to treat pregnancy- induced hypertension)

    Legal status

    ℞ ( Prescription only)

    Routes of

    administration Oral ( capsules, tablets, oral solution)

    Pharmacokinetic data

    Bioavailability Variably absorbed from GI tract. Bioavailability ~ 70%

    Metabolism does not undergo significant metabolism ( >95% excreted unchanged in urine) [ 1]

    Biological half- life 5.6–14.8 h

    Excretion Primarily excreted unchanged in urine

    Identifiers

    CAS Registry Number 58- 93- 5 Yes

    ATC code C03AA03

    PubChem CID: 3639

    IUPHAR/ BPS 4836

    DrugBank DB00999 Yes

    ChemSpider 3513 Yes

    UNII 0J48LPH2TH Yes

    KEGG D00340 Yes

    ChEBI CHEBI: 5778

    ChEMBL CHEMBL435 Yes

    Chemical data

    Formula C7H8ClN3O4S2

    Molecular mass 297.74 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 9, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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