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Hydrochlorothiazide Usp Ip Bp Ep Manufacturer - India

price: contact company for price

CERTIFICATE OF ANALYSIS

Product Name HYDROCHLOROTHIAZIDE CAS No:

Batch No: HYD/ 011114 A. R. No 14/ FP/ HYD/ 0111

Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

Batch Quantity 100 kg Date of Retest Jan- 2017

Sr. No Test Results Acceptance Criteria

1. Appearance Complies White to off- white crystalline powder.

2. Identification Complies

Complies IR

UV

3. Solubility Complies Very slightly soluble in water, soluble in

acetone, sparingly soluble in ethanol ( 96 per

cent) . It dissolves in dilute solutions of alkali

hydroxides.

4. Chloride Complies NMT 0.035%

5. Selenium Complies NMT 0.003%

6. Related substances

Any peak

Sum of peak

0.03%

0.09%

NMT 0.5%

NMT 0.9%

7. Heavy metals Complies NMT 0.001%

8. Residue on ignition 0.09% NMT 0.1%

9. 4- Amino- 6- chloro- 1.3-

- Benzenedisulfonamide 0.35% NMT 1%

10. Loss on drying 0.21% NMT 0.5%

11. Organic volatile impurities Complies Meets the requirements

12. Assay 99.39% 98% to 102%

Hydrochlorothiazide

Hydrochlorothiazide- 2D- skeletal. png

Hydrochlorothiazide- from- xtal- 3D- balls. png

Systematic ( IUPAC) name

6- chloro- 1, 1- dioxo- 3, 4- dihydro- 2H- 1, 2, 4- benzothiadiazine- 7- sulfonamide

Clinical data

Trade names Apo- hydro, Aquazide h, Dichlotride among others, Oretic

AHFS/ Drugs. com monograph

MedlinePlus a682571

Pregnancy

category

B ( D if used to treat pregnancy- induced hypertension)

Legal status

℞ ( Prescription only)

Routes of

administration Oral ( capsules, tablets, oral solution)

Pharmacokinetic data

Bioavailability Variably absorbed from GI tract. Bioavailability ~ 70%

Metabolism does not undergo significant metabolism ( >95% excreted unchanged in urine) [ 1]

Biological half- life 5.6–14.8 h

Excretion Primarily excreted unchanged in urine

Identifiers

CAS Registry Number 58- 93- 5 Yes

ATC code C03AA03

PubChem CID: 3639

IUPHAR/ BPS 4836

DrugBank DB00999 Yes

ChemSpider 3513 Yes

UNII 0J48LPH2TH Yes

KEGG D00340 Yes

ChEBI CHEBI: 5778

ChEMBL CHEMBL435 Yes

Chemical data

Formula C7H8ClN3O4S2

Molecular mass 297.74 g/ mol


Company Contact:


  • Phone: 912406641875

  • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

  • Email: Email


Published date: September 9, 2015 -

  • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

    Pharmaceuticals of global quality standards to Pharma Companies all over

    the world. In our warehouse facilities, approved by FDA. we supply

    Pharmaceutical Finished products, Dental products and Active

    Pharmaceutical Ingredients.

    We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

    We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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