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  • Imipramine Hydrochloride Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Imipramine Hydrochloride USP CAS No: 113- 52- 0

    Batch No: IMI/ 030313 A. R. No 13/ FP/ IMI/ 0303

    Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

    Batch Quantity 165 kg Date of Retest Jan- 2016

    Sr. No Test Results Acceptance Criteria

    1. Appearance

    2. Solubility

    3. Identification

    Complies a) By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.

    Complies b) By HPLC: Retention time of the principle peak in the chromatogram obtained with sample solution should match with that of the principle peak in chromatogram obtained with standard solution.

    4. Related Substances

    Individual Impurity Total Impurity

    0.076 %

    0.29%

    NMT 0.2%

    NMT 1.0%

    5. Loss on drying 0.35% NMT 0.5%

    6. Heavy Metals Complies 10ppm

    7. Residue On Ignition 0.034% NMT 0.1%

    8. Assay HPLC 99.26% 98.0% –102.0%

    9. Melting Temperature 171º 170°–174°

    Imipramine

    Imipramine. svg

    Imipramine- 3D- balls. png

    Systematic ( IUPAC) name

    3- ( 10, 11- dihydro- 5H- dibenzo[ b, f] azepin- 5- yl) - N, N- dimethylpropan- 1- amine

    Clinical data

    Trade names Tofranil

    AHFS/ Drugs. com monograph

    MedlinePlus a682389

    Pregnancy

    category

    AU: C

    US: N ( Not classified yet)

    Legal status

    AU: Prescription Only ( S4)

    CA: ℞ - only

    UK: Prescription- only ( POM)

    US: ℞ - only

    Routes of

    administration Oral

    Pharmacokinetic data

    Bioavailability 94- 96% [ 1]

    Protein binding 86% [ 2]

    Metabolism Hepatic ( CYP1A2, CYP2C19, CYP2D6)

    Main active metabolite desipramine[ 2]

    Biological half- life 20 hours[ 2]

    Excretion Renal ( 80% ) , Faecal ( 20% ) ( mostly as inactive metabolites) [ 2]

    Identifiers

    CAS Registry Number 50- 49- 7 Yes

    ATC code N06AA02

    PubChem CID: 3696

    IUPHAR/ BPS 357

    DrugBank DB00458 Yes

    ChemSpider 3568 Yes

    UNII OGG85SX4E4 Yes

    KEGG D08070 Yes

    ChEBI CHEBI: 47499 Yes

    ChEMBL CHEMBL11 Yes

    Chemical data

    Formula C19H24N2

    Molecular mass 280.407 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 9, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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