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  • Indomethacin Sodium Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Indomethacin Sodium USP CAS No: 7681- 54- 1

    Batch No: IND/ 030313 A. R. No 13/ FP/ IND/ 0303

    Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

    Batch Quantity 165 kg Date of Retest Jan- 2016

    Sr. No Test Results Acceptance Criteria

    1. Appearance

    2. Solubility

    3. Identification

    Complies a) Thin- Layer Chromatographic Identification Test: The intensity and RF value of the principal spot of the Sample solution correspond to those of the Standard solution.

    Complies b) By HPLC: Retention time of the principle peak in the chromatogram obtained with sample solution should match with that of the principle peak in chromatogram obtained with standard solution.

    4. Related Substances

    Individual Impurity Total Impurity

    0.18%

    0.32%

    NMT 0.5%

    NMT 1.0%

    5. Loss on drying 12.2% 11.5% –13.5%

    6. Heavy Metals Complies 20ppm

    7. Assay HPLC 99.34% 98.0% –101.0%

    Indometacin

    Indometacin skeletal. svg

    Systematic ( IUPAC) name

    2- { 1- [ ( 4- Chlorophenyl) carbonyl] - 5- methoxy- 2- methyl- 1H- indol- 3- yl} acetic acid

    Clinical data

    Trade names Indocid, Indocin

    AHFS/ Drugs. com monograph

    Licence data US FDA: link

    Pregnancy

    category

    AU: C

    C/ D ( US)

    Legal status

    AU: Prescription Only ( S4)

    CA: ℞ - only

    UK: Prescription- only ( POM)

    US: ℞ - only

    Routes of

    administration Oral, rectal, IV, topical

    Pharmacokinetic data

    Bioavailability ~100% ( oral) , 80–90% ( rectal)

    Protein binding 99% [ 1]

    Metabolism Hepatic

    Biological half- life 2.6- 11.2 hours ( adults) , 12- 28 hours ( infants) [ 1]

    Excretion Renal 60% , faecal 33%

    Identifiers

    CAS Registry Number 53- 86- 1 Yes

    ATC code C01EB03 M01AB01, M02AA23, S01BC01

    PubChem CID: 3715

    IUPHAR/ BPS 1909

    DrugBank DB00328 Yes

    ChemSpider 3584 Yes

    UNII XXE1CET956 Yes

    KEGG D00141 Yes

    ChEBI CHEBI: 49662 Yes

    ChEMBL CHEMBL6 Yes

    PDB ligand ID IMN ( PDBe, RCSB PDB)

    Chemical data

    Formula C19H16ClNO4

    Molecular mass 357.787 g. mol− 1


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 9, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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