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  • Irinotecan Hcl Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Irinotecan HCL CAS No: 136572- 09- 3

    Batch No: IRI/ 011114 A. R. No 14/ FP/ IRI/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies Pale yellow crystalline powder

    2. Solubility Complies Sparingly soluble in methanol Slightly soluble in water

    3. Identification Complies IR

    HPLC

    4. PH 4.5 3 to 5

    5. Melting point 253.9ºC to 254.6ºC 250ºC to 256ºC

    6. Heavy metals Complies NMT 20 PPM

    7. Specific rotation +70.2° +60° to +73°

    8. Absorption. at. 430nm 0.15% NMT 0.17%

    9. Total chloride 5.4% 5.2% to 6.0%

    10. Sulphated ash 0.6% NMT 1.0%

    11. Water 8.4% 8% to 9%

    12. Microbial contamination Complies NMT 100 cfu/ g

    Irinotecan

    Irinotecan. svg

    Irinotecan ball- and- stick. png

    Systematic ( IUPAC) name

    ( S) - 4, 11- diethyl- 3, 4, 12, 14- tetrahydro- 4- hydroxy-

    3, 14- dioxo1H- pyrano[ 3’, 4’: 6, 7] - indolizino[ 1, 2- b] quinolin-

    9- yl- [ 1, 4’bipiperidine] - 1’- carboxylate

    Clinical data

    Trade names Camptosar

    AHFS/ Drugs. com monograph

    MedlinePlus a608043

    Pregnancy

    category

    D ( Australia, United States)

    Legal status

    POM ( UK) , ℞ - only ( U. S. )

    Routes of

    administration Intravenous

    Pharmacokinetic data

    Bioavailability NA

    Metabolism Hepatic glucuronidation

    Biological half- life 6 to 12 hours

    Excretion Biliary and renal

    Identifiers

    CAS Registry Number 100286- 90- 6 Yes

    ATC code L01XX19

    PubChem CID: 60838

    IUPHAR/ BPS 6823

    DrugBank DB00762 Yes

    ChemSpider 54825 Yes

    UNII 7673326042 Yes

    KEGG D08086 Yes

    ChEMBL CHEMBL481 Yes

    Chemical data

    Formula C33H38N4O6

    Molecular mass 586.678 g/ mol ( Irinotecan)

    623.139 g/ mol ( Irinotecan hydrochloride)

    677.185 g/ mol ( Irinotecan hydrochloride trihydrate)


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 9, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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