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Levothyroxine Sodium Usp Ip Bp Ep Manufacturer - India

price: contact company for price

CERTIFICATE OF ANALYSIS

Product Name Levothyroxine Sodium CAS No: 55- 03- 8

Batch No: LEV/ 011114 A. R. No 14/ FP/ LEV/ 0111

Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

Batch Quantity 100 kg Date of Retest Jan- 2017

Sr. No Test Results Acceptance Criteria

1. Appearance Complies Light yellow to buff- colored

2. Specific rotation - 5.3° - 5° to - 6°

3. Water 7.6 NMT 11.0%

4. Lodides content 0.08% NMT 0.08%

5. PH 9.0 8.5 to 9.5

6. Assay

Levothyroxine Sodium

Liothyronine

98.5%

0.6%

97% to 103%

NMT 2.0%

.

Levothyroxine

Levothyroxine 200. svg

Levothyroxine 3D ball. png

Names

IUPAC name

( S) - 2- Amino- 3- [ 4- ( 4- hydroxy- 3, 5- diiodophenoxy) - 3, 5- diiodophenyl] propanoic acid

Other names

3, 5, 3' , 5' - Tetraiodo- L- thyronine

Identifiers

CAS Registry Number

51- 48- 9 Yes

ATC code H03AA01

ChEBI CHEBI: 18332 Yes

ChEMBL ChEMBL1624 Yes

ChemSpider 5614 Yes

DrugBank DB00451 Yes

InChI[ show]

IUPHAR/ BPS

2635

Jmol- 3D images Image

MeSH Thyroxine

PubChem 5819

SMILES[ show]

UNII Q51BO43MG4

Pharmacology

Legal status

℞ ( Prescription only)

Pregnancy

category

US: A ( No risk in human studies)

Routes of

administration

Oral, intravenous

Pharmacokinetics:

Bioavailability

~100%

Metabolism

Mainly in liver, kidneys, brain and muscles

Biological half- life

ca. 7 days ( in hyperthyroidism 3–4 days, in hypothyroidism 9–10 days)

Excretion

Through feces and urine

Properties

Chemical formula

C15H11I4NO4

Molar mass 776.87 g· mol− 1

Melting point 231 to 233 °C ( 448 to 451 °F; 504 to 506 K) [ 2]

Solubility in water

Slightly soluble ( 0.105 mg· l− 1 at 25 °C) [ 1]

Hazards

S- phrases S22- S24/ 25

Related compounds

Triiodothyronine ( tri- iodated)

Thyronine ( without iodine)

Except where otherwise noted, data are given for materials in their standard state ( at 25 °C [ 77 °F] , 100 kPa) .


Company Contact:


  • Phone: 912406641875

  • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

  • Email: Email


Published date: September 9, 2015 -

  • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

    Pharmaceuticals of global quality standards to Pharma Companies all over

    the world. In our warehouse facilities, approved by FDA. we supply

    Pharmaceutical Finished products, Dental products and Active

    Pharmaceutical Ingredients.

    We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

    We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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