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Metamizole Sodium Usp Ip Bp Ep Manufacturer - India

price: contact company for price

CERTIFICATE OF ANALYSIS

Product Name METAMIZOLE SODIUM CAS No:

Batch No: MET/ 011114 A. R. No 14/ FP/ MET/ 0111

Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

Batch Quantity 100 kg Date of Retest Jan- 2017

Sr. No Test Results Acceptance Criteria

1. Appearance Complies White to almost white crystalline powder

2. Identification

Complies Comparing with the spectrum obtained with CRS

Positive

Reaction of sodium

3. Appearance of solution Complies Meets the requirements

4. PH Complies Meets the requirements

5. Related substances

Impurity C

Impurity A, B, D

Total impurities

0.01%

Negative

0.09%

NMT 0.5%

NMT 0.2%

6. Sulfates 0.1% NMT 0.1%

Metamizole

Metamizole2DACS. svg

Metamizole3DanJ- fix. gif

Systematic ( IUPAC) name

[ ( 2, 3- dihydro- 1, 5- dimethyl- 3- oxo- 2- phenyl- 1H- pyrazol- 4- yl) methylamino] methanesulfonic acid

Clinical data

Trade names Originally Novalgin, [ 3] now generic[ 4]

AHFS/ Drugs. com International Drug Names

Pregnancy

category

None assigned; no evidence of teratogenicity in animal studies, but use in the third trimester may cause adverse effects in the newborn or ductus arteriosus ( a heart defect) due to its weak NSAID activity. [ 1] [ 2]

Legal status

Over- the- counter ( some countries, see text) ; prescription- only ( others) ; withdrawn ( others)

Routes of

administration Oral, IM, IV, rectal

Pharmacokinetic data

Bioavailability 100% ( active metabolites) [ 5]

Protein binding 48% - 58% ( active metabolites) [ 5]

Metabolism Liver[ 5]

Biological half- life 14 minutes ( parent compound; parenteral) ; [ 2] metabolites: 2–4 hours[ 5]

Excretion Urine ( 96% , IV; 85% , oral) , faeces ( 4% , IV) . [ 2]

Identifiers

CAS Registry Number 68- 89- 3 ( sodium salt)

ATC code N02BB02

PubChem CID: 80254

DrugBank DB04817 Yes

ChemSpider 3000

UNII VSU62Z74ON Yes

ChEBI CHEBI: 59033 Yes

ChEMBL CHEMBL487894 Yes

Chemical data

Formula C13H17N3O4S

Molecular mass 311.357 g/ mol


Company Contact:


  • Phone: 912406641875

  • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

  • Email: Email


Published date: September 10, 2015 -

  • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

    Pharmaceuticals of global quality standards to Pharma Companies all over

    the world. In our warehouse facilities, approved by FDA. we supply

    Pharmaceutical Finished products, Dental products and Active

    Pharmaceutical Ingredients.

    We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

    We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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