Methenamine Usp Ip Bp Ep Manufacturer - Indiaprice: contact company for price
Product Name Methenamine, USP CAS No: 100- 97- 0
Batch No: MET/ 030313 A. R. No 13/ FP/ MET/ 0303
Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13
Batch Quantity 165 kg Date of Retest Jan- 2016
Sr. No Test Results Acceptance Criteria
Complies By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.
4. Loss on drying 1.1% NMT 2.0%
5. Heavy Metals Complies 10ppm
6. Residue On Ignition 0.065% NMT 0.1%
7. Assay HPLC 99.78% 99.0% –100.5%
Hexamine- 3D- balls. png
1, 3, 5, 7- Tetraazatricyclo[ ] decane
Urotropine; 1, 3, 5, 7- tetraazaadamantane, Formin, Aminoform
CAS Registry Number
100- 97- 0 Yes
ATC code J01XX05
ChEBI CHEBI: 6824 Yes
ChemSpider 3959 Yes
EC number 202- 905- 8
Jmol- 3D images Image
KEGG D00393 Yes
UNII J50OIX95QV Yes
Molar mass 140.186 g/ mol
Appearance White crystalline solid
Density 1.33 g/ cm3 ( at 20 °C)
Melting point 280 °C ( 536 °F; 553 K) ( sublimes)
Solubility in water
85.3 g/ 100 mL
Acidity ( pKa) 4.89[ 1]
Main hazards Highly flammable, harmful
Flash point 250 °C ( 482 °F; 523 K)
410 °C ( 770 °F; 683 K)
Except where otherwise noted, data are given for materials in their standard state ( at 25 °C [ 77 °F] , 100 kPa) .
Hexamethylenetetramine or methenamine is a heterocyclic organic compound with the formula ( CH2) 6N4. This white crystalline compound is highly soluble in water and polar organic solvents. It has a cage- like structure similar to adamantane. Wikipedia
Molar mass: 140.186 g/ mol
IUPAC ID: 1, 3, 5, 7- Tetraazatricyclo[ ] decane
Density: 1.33 g/ cm³
Boiling point: 280 °C
Soluble in: Water
Hexamethylenetetramine or methenamine is a heterocyclic organic compound with the formula ( CH2) 6N4. This white crystalline compound is highly soluble in water and polar organic solvents. It has a cage- like structure similar to adamantane. It is useful in the synthesis of other chemical compounds, e. g. plastics, pharmaceuticals, rubber additives. It sublimes in a vacuum at 280 °C.
Hexamethylenetetramine is prepared industrially by combining formaldehyde and ammonia. The reaction can be conducted in gas- phase and in solution.
The molecule has a symmetric tetrahedral cage- like structure, similar to adamantane, whose four ' corners' are nitrogen atoms and ' edges' are methylene bridges. Although the molecular shape defines a cage, no void space is available at the interior for binding other atoms or molecules, unlike crown ethers or larger cryptand structures.
The molecule behaves like an amine base, undergoing protonation and N- alkylation.
When treated with nitric acid, hexamine forms the explosive RDX ( known chemically as cyclotrimethylenetrinitramine) . Hexamine reacts with hydrogen peroxide to form hexamethylene triperoxide diamine or dilute sulfuric acid.
The dominant use of hexamethylenetetramine is in the production of powdery or liquid preparations of phenolic resins and phenolic resin moulding compounds, where it is added as a hardening component. These products are used as binders, e. g. in brake and clutch linings, abrasive products, non- woven textiles, formed parts produced by moulding processes, and fireproof materials.
As the mandelic acid salt ( generic methenamine mandelate, USP) it is used for the treatment of urinary tract infection. It decomposes at an acidic pH to form formaldehyde and ammonia, and the formaldehyde is bactericidal; the mandelic acid adds to this effect. Urinary acidity is typically ensured by co- administering vitamin C ( ascorbic acid) or ammonium chloride. Its use had temporarily been reduced in the late 1990s, due to adverse effects, particularly chemically- induced hemorrhagic cystitis in overdose, but its use has now been re- approved because of the prevalence of antibiotic resistance to more commonly used drugs. This drug is particularly suitable for long- term prophylactic treatment of urinary tract infection, because bacteria do not develop resistance to formaldehyde. It should not be used in the presence of renal insufficiency.
- Posted By: SWAPNROOP DRUGS AND PHARMACEUTICALS
- Phone: 912406641875
- Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India
- Website: http://www.apisupplier.com
Published date: September 10, 2015 -
- Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &
Pharmaceuticals of global quality standards to Pharma Companies all over
the world. In our warehouse facilities, approved by FDA. we supply
Pharmaceutical Finished products, Dental products and Active
We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.
We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.
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