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  • Methylprednisolone Hemisuccinate Usp Ip Ep Bp Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Methylprednisolone Hemisuccinate USP CAS No: 2921- 57- 5

    Batch No: MET/ 030313 A. R. No 13/ FP/ MET/ 0303

    Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

    Batch Quantity 165 kg Date of Retest Jan- 2016

    Sr. No Test Results Acceptance Criteria

    1. Appearance

    2. Solubility

    3. Identification

    Complies By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.

    4. Related Substances

    Individual Impurity Total Impurity

    0.85%

    1.32%

    NMT 1.0%

    NMT 2.0%

    5. Specific Optical Rotation at 20 0 C ( Anhydrous Basis) +89º Between +87° to +95°

    6. Loss on drying 0.45% NMT 1.0%

    7. Residue On Ignition 0.065% NMT 0.2%

    8. Assay HPLC 99.23% 97.0% –103.0%

    Methylprednisolone

    Methylprednisolone. svg

    Methylprednisolone. png

    Systematic ( IUPAC) name

    ( 1S, 2R, 8S, 10S, 11S, 14R, 15S, 17S) - 14, 17- dihydroxy- 14- ( 2- hydroxyacetyl) - 2, 8, 15- trimethyltetracyclo[ ] heptadeca- 3, 6- dien- 5- one

    Clinical data

    Trade names Medrol, Meprolone

    AHFS/ Drugs. com monograph

    MedlinePlus a682795

    Licence data US FDA: link

    Pregnancy

    category

    AU: A

    US: C ( Risk not ruled out)

    Legal status

    UK: Prescription- only ( POM)

    US: ℞ - only

    Routes of

    administration IV, IM, IV Infusion, Oral, Rectal, Topical

    Pharmacokinetic data

    Protein binding 78%

    Metabolism liver primarily, kidney, tissues; CYP450: 3A4 substrate

    Biological half- life urine; Half- life: 18- 26h ( biological)

    Identifiers

    CAS Registry Number 83- 43- 2 Yes

    ATC code D07AA01 D07AC14, D10AA02, H02AB04

    PubChem CID: 6741

    IUPHAR/ BPS 7088

    DrugBank DB00959 Yes

    ChemSpider 6485 Yes

    UNII X4W7ZR7023 Yes

    KEGG D00407 Yes

    ChEBI CHEBI: 6888 Yes

    ChEMBL CHEMBL650 Yes

    Synonyms ( 6α , 11β ) - 11, 17, 21- trihydroxy- 6- methyl- pregna- 1, 4- diene- 3, 20- dione

    Chemical data

    Formula C22H30O5

    Molecular mass 374.471 g/ mol

    .

    General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 10, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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