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  • Naproxen Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Naproxen USP CAS No: 22204- 53- 1

    Batch No: NAP/ 030313 A. R. No 13/ FP/ NAP/ 0303

    Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

    Batch Quantity 165 kg Date of Retest Jan- 2016

    Sr. No Test Results Acceptance Criteria

    1. Appearance

    2. Solubility

    3. Identification

    Complies By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.

    4. Specific Optical Rotation at 20 0 C ( Anhydrous Basis) +85.5º Between +83.0° to +89.5°

    5. Loss on drying 0.27% NMT 0.5%

    6. Heavy Metals Complies 20ppm

    7. Assay 100.12% 98.5% –101.5%

    .

    Naproxen

    Naproxen2DACS. svg

    Naproxen3d. png

    Systematic ( IUPAC) name

    ( +) - ( S) - 2- ( 6- methoxynaphthalen- 2- yl)

    propanoic acid

    Clinical data

    Trade names Aleve, Anaprox, Apronax, Naprelan, Naprosyn

    AHFS/ Drugs. com monograph

    MedlinePlus a681029

    Licence data US Daily Med: link

    Pregnancy

    category

    AU: C

    US: C ( Risk not ruled out)

    Legal status

    AU: Pharmacy Only ( S2)

    CA: OTC

    UK: Pharmacy medicines

    US: OTC

    In Australia it is only Schedule 2 when in preparations containing no more than 15 days' supply. Otherwise it is schedule 4 ( prescription- only) . [ 1]

    Routes of

    administration Oral.

    Pharmacokinetic data

    Bioavailability 95% ( oral)

    Protein binding 99%

    Metabolism Hepatic ( to 6- desmethylnaproxen)

    Biological half- life 12–24 hours

    Excretion Renal

    Identifiers

    CAS Registry Number 22204- 53- 1 Yes

    ATC code G02CC02 M01AE02, M02AA12

    PubChem CID: 156391

    DrugBank DB00788 Yes

    ChemSpider 137720 Yes

    UNII 57Y76R9ATQ Yes

    KEGG D00118 Yes

    ChEBI CHEBI: 7476 Yes

    ChEMBL CHEMBL154 Yes

    Chemical data

    Formula C14H14O3

    Molecular mass 230.259 g/ mol

    . .

    Naproxen / nə ˈ prɒ ksə n/ ( INN; brand names: Aleve, Naprosyn and many others) , is a non- selective COX inhibitor; usually sold as the sodium salt, is a nonsteroidal anti- inflammatory drug ( NSAID) of the propionic acid class ( which puts it in the same class as ibuprofen) and is commonly used for relief of a wide variety of pain, fever, swelling and stiffness. [ 2] [ 3] : 665, 673

    It is the preferred NSAID for long- term use in people with a high risk of cardiovascular ( for example, heart attacks or strokes) complications, [ 3] : 665 due to its relatively low risk of causing such complications. Naproxen has an intermediate risk of causing stomach ulcers as compared with ibuprofen, which is low risk, and indometacin, which is high risk. [ 4] In order to reduce the risk of stomach ulceration, it is often combined with a proton- pump inhibitor ( a medication that reduces the production of stomach acid) during long- term treatment, in those with pre- existing stomach ulcers, or a history of developing stomach ulcers while on NSAIDs


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 10, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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