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Neostigmine Methylsulfate Usp Ip Bp Ep Manufacturer - India

price: contact company for price

CERTIFICATE OF ANALYSIS

Product Name Neostigmine Methylsulfate USP CAS No: 51- 60- 5

Batch No: NEO/ 030313 A. R. No 13/ FP/ NEO/ 0303

Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

Batch Quantity 165 kg Date of Retest Jan- 2016

Sr. No Test Results Acceptance Criteria

1. Appearance

2. Solubility

3. Identification

Complies a) By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.

Complies b) Sulfate: Meets the requirements.

4. Loss on drying 0.65% NMT 1.0%

5. Residue On Ignition 0.032% NMT 0.1%

6. Assay 99.37% 98.0% –102.0%

7. Melting Temperature 145º 144°–149°

.

Neostigmine Ion V. 1. svg

Neostigmine ball- and- stick. png

Systematic ( IUPAC) name

3- { [ ( dimethylamino) carbonyl] oxy} - N, N, N- trimethylbenzenaminium

Clinical data

Trade names Prostigmin

AHFS/ Drugs. com monograph

Legal status

UK: Prescription- only ( POM)

Pharmacokinetic data

Bioavailability Unclear, probably less than 5%

Metabolism Slow hydrolysis by acetylcholinesterase and also by plasma esterases

Biological half- life 50–90 minutes

Excretion Unchanged drug ( up to 70% ) and alcoholic metabolite ( 30% ) are excreted in the urine

Identifiers

CAS Registry Number 59- 99- 4 Yes

ATC code N07AA01 S01EB06 QA03AB93

PubChem CID: 4456

DrugBank DB01400 Yes

ChemSpider 4301 Yes

UNII 3982TWQ96G Yes

KEGG D08261 Yes

ChEBI CHEBI: 7514 Yes

ChEMBL CHEMBL54126

Chemical data

Formula C12H19N2O2

Molecular mass 223.294 g/ mol

. .

Neostigmine was first synthesized by Aeschlimann and Reinert in 1931[ 1] and was patented by Aeschliman in 1933. [ 2]

Neostigmine is made by first reacting 3- dimethylaminophenol with N- dimethylcarbamoyl chloride, which forms a dimethylcarbamate. Next, that product is alkylated using dimethylsulfate, which forms neostigmine. [ 3]


Company Contact:


  • Phone: 912406641875

  • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

  • Email: Email


Published date: September 10, 2015 -

  • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

    Pharmaceuticals of global quality standards to Pharma Companies all over

    the world. In our warehouse facilities, approved by FDA. we supply

    Pharmaceutical Finished products, Dental products and Active

    Pharmaceutical Ingredients.

    We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

    We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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