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  • Phenobarbital Sodium Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Phenobarbital Sodium USP CAS No: 57- 30- 7

    Batch No: PHE/ 030313 A. R. No 13/ FP/ PHE/ 0303

    Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

    Batch Quantity 165 kg Date of Retest Jan- 2016

    Sr. No Test Results Acceptance Criteria

    1. Appearance

    2. Solubility

    3. Identification

    Complies a) Sodium: Meets the requirements.

    Complies b) By HPLC: Retention time of the principle peak in the chromatogram obtained with sample solution should match with that of the principle peak in chromatogram obtained with standard solution.

    4. pH 6.3 Between 9.2–10.2

    5. Loss on drying 4.2% NMT 7.0%

    6. Heavy Metals Complies 30ppm

    7. Bacterial Endotoxins Test 0.3 EU/ mg NMT 0.8 USP EU/ mg

    8. Assay HPLC 99.37% 98.5% –101.0%

    2D chemical structure of phenobarbital

    3D ball- and- stick model of phenobarbital

    Systematic ( IUPAC) name

    5- Ethyl- 5- phenyl- 1, 3- diazinane- 2, 4, 6- trione

    Clinical data

    Trade names Luminal

    AHFS/ Drugs. com monograph

    MedlinePlus a682007

    Pregnancy

    category

    AU: D

    US: D ( Evidence of risk)

    Legal status

    AU: Prescription Only ( S4)

    UK: Class B

    US: Schedule IV

    Dependence

    liability High

    Routes of

    administration Oral ( PO) , rectal ( PR) , parenteral ( intramuscular and intravenous)

    Pharmacokinetic data

    Bioavailability >95%

    Protein binding 20 to 45%

    Metabolism Hepatic ( mostly CYP2C19)

    Onset of action within 5 min ( IV) and 30 min ( PO) [ 1]

    Biological half- life 53 to 118 hours

    Duration of action 4 hrs[ 1] to 2 days[ 2]

    Excretion Renal and fecal

    Identifiers

    CAS Registry Number 50- 06- 6 Yes

    ATC code N05CA24 N03AA02

    PubChem CID: 4763

    IUPHAR/ BPS 2804

    DrugBank DB01174 Yes

    ChemSpider 4599 Yes

    UNII YQE403BP4D Yes

    KEGG D00506 Yes

    ChEBI CHEBI: 8069 Yes

    ChEMBL CHEMBL40 Yes

    Chemical data

    Formula C12H12N2O3

    Molecular mass 232.235 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 12, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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