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Spironolactone Usp Ip Bp Ep Manufacturer - India

price: contact company for price

CERTIFICATE OF ANALYSIS

Product Name Spironolactone USP CAS No: 52- 01- 7

Batch No: SPI/ 030313 A. R. No 13/ FP/ SPI/ 0303

Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

Batch Quantity 165 kg Date of Retest Jan- 2016

Sr. No Test Results Acceptance Criteria

1. Appearance

2. Solubility

3. Identification

Complies By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.

4. Specific Optical Rotation at 20 0 C ( Anhydrous Basis) - 34º Between - 33° to - 37°

5. Loss on drying 0.23% NMT 0.5%

6. Assay HPLC 98.17% 97.0% –103.0%

7. Melting Temperature 201º Between 198° and 209°

Spironolactone

Skeletal formula of spironolactone

Ball- and- stick model of the spironolactone molecule

Systematic ( IUPAC) name

7α - acetylthio- 3- oxo- 17α - pregn- 4- ene- 21, 17- carbolactone

or

17- hydroxy- 7α - mercapto- 3- oxo- 17α - pregn- 4- ene- 21- carboxylic acid, γ - lactone acetate

Clinical data

Trade names Aldactone

AHFS/ Drugs. com monograph

MedlinePlus a682627

Pregnancy

category

AU: B3

US: C ( Risk not ruled out)

Legal status

UK: Prescription- only ( POM)

US: ℞ - only

Routes of

administration Oral

Pharmacokinetic data

Protein binding 90% +[ 1]

Metabolism Hepatic CYP450

Biological half- life 1.3- 2 hours

Excretion Urine, bile

Identifiers

CAS Registry Number 52- 01- 7 Yes

ATC code C03DA01

PubChem CID: 5833

IUPHAR/ BPS 2875

DrugBank DB00421 Yes

ChemSpider 5628 Yes

UNII 27O7W4T232 Yes

KEGG D00443 Yes

ChEBI CHEBI: 9241 Yes

ChEMBL CHEMBL1393 Yes

Chemical data

Formula C24H32O4S

Molecular mass 416.574 g/ mol


Company Contact:


  • Phone: 912406641875

  • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

  • Email: Email


Published date: September 14, 2015 -

  • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

    Pharmaceuticals of global quality standards to Pharma Companies all over

    the world. In our warehouse facilities, approved by FDA. we supply

    Pharmaceutical Finished products, Dental products and Active

    Pharmaceutical Ingredients.

    We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

    We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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