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  • Ticagrelor Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Ticagrelor CAS No: 274693- 27- 5

    Batch No: TIC/ 011114 A. R. No 14/ FP/ TIC/ 0111

    Date of Manufacture Nov- 2014 Date of Analysis 02- 11- 14

    Batch Quantity 100 kg Date of Retest Jan- 2017

    Sr. No Test Results Acceptance Criteria

    1. Appearance Complies White to off white crystalline powder

    2. Identification Complies

    Complies IR

    HPLC

    3. Loss on drying 0.24% NMT 0.5%

    4. Melting point 151.6°C to 152.1°C 146°C to 153°C

    5. Optical rotation - 53.5.0° Methanol C=1 - 40- - 60 0°

    6. Residue on Ignition 0.1% NMT 0.5%

    7. Heavy metal 20 PPM NMT 20 PPM

    8. Related substance

    Single impurity

    Total impurities

    0.08%

    0.4

    NMT 0.5%

    NMT 1.0%

    9. Residual Solvent 700 PPM

    Not detected

    19.8 PPM Methanol<3000 700ppm

    Ethanol<5000 ND

    Acetone<5000

    N( CH3CH2) 3<300

    10. Assay ( HPLC) 99.6% NLT 99.0%

    Ticagrelor. svg

    Ticagrelor ball- and- stick animation. gif

    Systematic ( IUPAC) name

    ( 1S, 2S, 3R, 5S) - 3- [ 7- [ ( 1R, 2S) - 2- ( 3, 4- Difluorophenyl) cyclopropylamino] - 5- ( propylthio) - 3H- [ 1, 2, 3] triazolo[ 4, 5- d] pyrimidin- 3- yl] - 5- ( 2- hydroxyethoxy) cyclopentane- 1, 2- diol

    Clinical data

    Trade names Brilinta, Brilique, Possia

    AHFS/ Drugs. com monograph

    MedlinePlus a611050

    Licence data EMA: Link, US FDA: link

    Pregnancy

    category

    US: C ( Risk not ruled out)

    Legal status

    US: ℞ - only

    Routes of

    administration Oral

    Pharmacokinetic data

    Bioavailability 36%

    Protein binding >99.7%

    Metabolism Hepatic ( CYP3A4)

    Biological half- life 7 hrs ( ticagrelor) , 8.5 hrs ( active metabolite AR- C124910XX)

    Excretion Biliary

    Identifiers

    CAS Registry Number 274693- 27- 5 Yes

    ATC code B01AC24

    PubChem CID: 9871419

    IUPHAR/ BPS 1765

    ChemSpider 8047109

    UNII GLH0314RVC Yes

    KEGG D09017 Yes

    ChEMBL CHEMBL398435

    Synonyms AZD- 6140

    Chemical data

    Formula C23H28F2N6O4S

    Molecular mass 522.567 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 14, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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