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  • Warfarin Sodium Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Warfarin Sodium USP CAS No: 129- 06- 6

    Batch No: WAR/ 030313 A. R. No 13/ FP/ WAR/ 0303

    Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

    Batch Quantity 165 kg Date of Retest Jan- 2016

    Sr. No Test Results Acceptance Criteria

    1. Appearance

    2. Solubility

    3. Identification

    Complies a) By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.

    Complies b) By HPLC: Retention time of the principle peak in the chromatogram obtained with sample solution should match with that of the principle peak in chromatogram obtained with standard solution.

    Complies c) Sodium: The filtrate obtained in Identification test A responds to the flame test for sodium.

    4. Related Substances

    Individual Impurity Total Impurity

    0.12%

    0.26%

    NMT 0.3%

    NMT 1.0%

    5. pH 7.9 Between 7.2–8.3

    6. Heavy Metals Complies NMT 10ppm

    7. Water Content by KF 1.7% NMT 4.5%

    8. Absorbance In Alkaline Solution 0.655 NMT 0.1

    9. Assay HPLC 98.48% 97.0% –102.0%

    Warfarin. svg

    Warfarin ball- and- stick model. png

    Systematic ( IUPAC) name

    ( RS) - 4- Hydroxy- 3- ( 3- oxo- 1- phenylbutyl) - 2H- chromen- 2- one

    Clinical data

    Trade names Coumadin, Jantoven, Marevan

    AHFS/ Drugs. com monograph

    MedlinePlus a682277

    Licence data US FDA: link

    Pregnancy

    category

    AU: D

    US: X ( Contraindicated)

    Legal status

    AU: Prescription Only ( S4)

    CA: ℞ - only

    UK: Prescription- only ( POM)

    US: ℞ - only

    Routes of

    administration Oral or intravenous

    Pharmacokinetic data

    Bioavailability 79- 100% ( Oral) [ 1]

    Protein binding 99% [ 2]

    Metabolism Hepatic: CYP2C9, 2C19, 2C8, 2C18, 1A2 and 3A4[ 2]

    Biological half- life 20- 60 hours ( mean: 40 hours) [ 2]

    Excretion Renal ( 92% ) [ 2]

    Identifiers

    CAS Registry Number 81- 81- 2 YesI

    ATC code B01AA03

    PubChem CID: 54678486

    IUPHAR/ BPS 6853

    DrugBank DB00682

    ChemSpider 10442445 Yes

    UNII 5Q7ZVV76EI Yes

    KEGG D08682 Yes

    ChEBI CHEBI: 10033 Yes

    ChEMBL CHEMBL1464

    Chemical data

    Formula C19H16O4

    Molecular mass 308.33 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 14, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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