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  • Zidovudine Usp Ip Bp Ep Manufacturer - India

    price: contact company for price

    CERTIFICATE OF ANALYSIS

    Product Name Zidovudine USP CAS No: 30516- 87- 1

    Batch No: ZID/ 030313 A. R. No 13/ FP/ ZID/ 0303

    Date of Manufacture Feb- 2013 Date of Analysis 02- 02- 13

    Batch Quantity 165 kg Date of Retest Jan- 2016

    Sr. No Test Results Acceptance Criteria

    1. Appearance

    2. Solubility

    3. Identification

    Complies a) By IR Spectrum: The infrared absorption spectrum of the test sample exhibits maxima only at the same wavelengths as that of the working standard.

    Complies b) By HPLC: Retention time of the principle peak in the chromatogram obtained with sample solution should match with that of the principle peak in chromatogram obtained with standard solution.

    4. Related Substances

    Individual Impurity Total Impurity

    0.64%

    1.17%

    NMT 1.0%

    NMT 3.0%

    5. Specific Optical Rotation at 20 0 C ( Anhydrous Basis) +61º Between +60.5° and +63°

    6. Water Content by KF 0.7% NMT 1.0%

    7. Residue On Ignition 0.086% NMT 0.25%

    8. Assay HPLC 98.38% 97.0% –102.0%

    Zidovudine ( INN)

    Zidovudine. svg

    Zidovudine- 3D- balls. png

    Systematic ( IUPAC) name

    1- [ ( 2R, 4S, 5S) - 4- Azido- 5- ( hydroxymethyl) oxolan- 2- yl] - 5- methylpyrimidine- 2, 4- dione[ 1]

    Clinical data

    Trade names Retrovir

    AHFS/ Drugs. com monograph

    Pregnancy

    category

    AU: B3

    US: C ( Risk not ruled out) ( AZT)

    Legal status

    ℞ ( Prescription only)

    Routes of

    administration Oral, serum, suppository

    Pharmacokinetic data

    Bioavailability Complete absorption, following first- pass metabolism systemic availability 75% ( range 52 to 75% )

    Protein binding 30 to 38%

    Metabolism Hepatic

    Biological half- life 0.5 to 3 hours

    Excretion Renal/ Rectal

    Identifiers

    CAS Registry Number 30516- 87- 1 Yes

    ATC code J05AF01

    PubChem CID: 35370

    IUPHAR/ BPS 4825

    DrugBank DB00495 Yes

    ChemSpider 32555 Yes

    UNII 4B9XT59T7S Yes

    KEGG D00413

    ChEBI CHEBI: 10110

    ChEMBL CHEMBL129 Yes

    NIAID ChemDB 000001

    PDB ligand ID AZZ ( PDBe, RCSB PDB)

    Chemical data

    Formula C10H13N5O4

    Molecular mass 267.242 g/ mol


    Company Contact:


    • Phone: 912406641875

    • Address: PLOT NO: 04 JALGAON ROAD, HARSOOL, AURANGABAD, India

    • Email: Email


    Published date: September 14, 2015 -

    • Business Description: We, at SWAPNROOP, are committed to providing affordable Drugs &

      Pharmaceuticals of global quality standards to Pharma Companies all over

      the world. In our warehouse facilities, approved by FDA. we supply

      Pharmaceutical Finished products, Dental products and Active

      Pharmaceutical Ingredients.

      We, at SWAPNROOP, are committed to providing affordable Drugs & Pharmaceuticals of global quality standards to Pharma Companies all over the world. Our warehouse facilities is approved by FDA and we are specializes in sales and marketing of Pharmaceutical Finished products, Pharmaceutical Active Ingredients (API's) and Dental products, providing a wide range of quality and affordable products to a large number of pharmaceutical companies, reputed private and government/semi government organizations/ research centers as well as universities.

      We supply and market over 500 molecules and their combinations in multiple dosage forms, catering to patient needs in various therapies. These include Anti infectives, Cardiovascular, Pain management, Central Nervous System (CNS), Gastrointestinal, Respiratory, Dermatology, Orthopaedics, Nutritionals, Urology and Dental.

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