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  • Rutin By Sichuan Benepure Pharmaceutical Co Ltd - China

    price: contact company for price

    Product Name: Rutin

    Synonym: Rutoside, Vitamin P, Violaquereitrin

    Specification: NF11, DAB10, EP6

    CAS: 153- 18- 4

    Chemical Name: 3- { [ 6- 0- ( 6- deoxy- α- L- mannopyranosyl) - β- D- glucopyranosyl] oxy} - 2- ( 3, 4- dihyroxyphenyl) - 5, 7- dihydroxy- 4H- 1- benzopyran- 4- one.

    Molecular Formula: C27H30O16

    Molecular Weight: 610.51

    Physical Property:

    - Appearance: yellowish- needle - crystal ( in water)

    - Melting Point : 176- 8°C, 23D: +13.82°C ( ethanol) , 20D- 39.43 °C ( pyridine)

    - Solubility: 1g in 7ml of methanol, 8000ml of water, 200ml of boiling water

    - UVλ CH3OHmax nm: 258.361; IRνKBr max cm- 1: 3400( OH) , 1670( C=O) , 1620, 1520, 1470( C6H5- )

    Botanical source: Ruta graveolens L. , plant essential oil [ 2] ; Sophora japonica L. , main part of fruit [ 3, 4] ; Hypericum aseyron L. , full plant; Berchemia polyphylla Wall, var leioclada Hand. - Mazz. [ 5] ; Mallotus japonicus Muell. - Arg, leafs [ 6] ; Fagopyrum esculentum Moench seedling.

    Indications:

    - Anti- inflammatory action: apparent suppression of inflammation due to planted wool when the product is injected into abdominal cavity of rat [ 8] . Sodium rutin sulfate has very strong anti- inflammatory action to edema of rat [ 9] .

    - Actions like Vitamin P: maintain the strength of blood vessel, reduce its permeability and brittleness; degreasing action to liver fatty infiltration, especially together with glutathione.

    - Antiviral action: best suppression to phlyctenular stomatitis virus at product concentration of 200g/ ml [ 10, 11] .

    - Inhibition of aldehyde reductase: 95% inhibition at a concentration of 10- 5M [ 12] , which facilitates the treatment of diabetic cataract.

    - Toxicity: mice, intravenous injection, LD50 at 950mg/ kg.

    - Clinical use: for the prevention of intracerebral hemorrhage, hypertension, retinal hemorrhage, purpura and acute hemorrhagic nephrosonephritis; for treatment of chronic tracheitis with effective rate at 84.8% and 98% . Its derivative, troxerutin, or Venoruton, is applied clinically for burn, arthritis, and all kinds of blood vessel diseases. Commodity drug is available in abroad [ 14] , while the drug has been successfully developed in domestic. With Effective rate for the treatment of cerebrovascular diseases is 87.8% ; 88% for retinal edema and hemorrhage [ 3] .


    Company Contact:


    • Phone: 18980510772

    • Address: 99# Jirui 3rd Rd.,High-Tech District, Chengdu, China

    • Email: Email


    Published date: January 19, 2016 -

    • Business Description: Sichuan Benepure Pharmaceutical Co.,Ltd., is one of the professional

      manufacturer and exporter certified by cGMP, ISO series, Kosher and

      Halal, dedicated to the identifications, development and productions of

      botanical extracts and derivatives and APIs in China. With 11 year's

      high speed developing, strong R&D capabilities, advanced quality control

      and production technology, BENEPURE continue to make innovations with

      the specialty ingredients that serve the Nutraceutical, Pharmaceutical

      and Cosmetic industries.

      Natural Botanical Extract and derivatives: Grape Seed Ext., Grape Skin Ext.,Hesperidin, Hidrosmin,Diosmin, Hesperidin Methylchalcone, Methyl Hesperidin, Citrus Bioflavonoids, ect.

      API: Donepezil HCL,Tianeptine Sodium,Glycyl-L-Glutamine,Glycyl-L-Tyrosine,Clopidogrel sulfate,Ozagrel,Mildronate,Articaine hydrochloride,Prilocaine Base,Prilocaine HCL,Tetracaine Base,Tetracaine HCL,Lidocaine hydrochloride,Mepivacaine Base,ect.

      Intermediates.

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