Worldbid International Trade Leads Import Export b2b Marketplace

Home / Trade Leads Homepage / Category Offers / List Offers / Offer Details

View Offers to Buy: Equipment - Scientific

65 -- Laboratory equipment and supplies (OB1926049) (2007-09-21)

THIS IS A COMBINED SYNOPSIS / SOLICITATION NOTICE. This is a combined
synopsis / solicitation for commercial items, prepared in accordance with the
format of FAR 12.6 as supplemented with additional information included in
this notice. This announcement constitutes the only solicitation; proposals
are being requested and a written solicitation will not be issued.

The reference solicitation number is: NHLBI-PB(HL)-2007-235/CDM

This solicitation is issued as a Request for Quotation (RFQ).

This acquisition is being conducted in accordance with FAR Part 13, simplified
acquisition procedures and the resultant purchase order will include all
applicable provisions and clauses in effect through the Federal Acquisition
Circular 05-18. The total contracted dollar amount, including options will
not exceed $5 Million.

The acquisition is being conducted as a full and open competitive. This is a
small business set aside requirement. The North American Industry
Classification System (NAICS) code is 334516, associated small business size
standard is 500 employees.

The Government?s anticipated delivery date is June 30, 2008.

The delivery point is the National Institutes of Health, National Institute fo
Dental and Craniofacial Research, Laboratory of Sensory Biology, 9000
Rockville Pike, Bethesda, Maryland 20892.

A site visit is scheduled to be held on September 5, 2007 at 10:00 a.m. In
Building 10, Room 81A24, 9000 Rockville Pike, Bethesda, Maryland 20892. The
site visit is limited to two (2) attendees per perspective offeror and is not
expected to exceed one hour. The perspective officer is required to submit
any questions in writing to the Contract Specialist not later then twenty-four
hours preceding the site visit. The attendance to the site visit must be
confirmed by the perspective officer to the Contract Specialist on or before
Tuesday September 4, 2007 at 10:00 a.m. Eastern time.

The National Institutes of Health (NIH), National Heart, Lung, and Blood
Institute (NHLBI), Office of Acquisition (OA), for the National Institute of
Dental and Craniofacial Research (NIDCR) intend to award a purchase order for
one each, Custom 2-photon Imaging system. The Laboratory of Sensory Biology,
needs this custom made 2-photon Imaging System to enable use of this powerful
methodology for studies of the neural-circuitry, molecular and cellular basis
of sensory perception. The system shall provide precise and deep-imaging (0.-
3mm) of tissue including peripheral sensory organs, the neural ganglia and the
Central Nervous System. The system shall be capable of exploiting novel
genetically encoded optical switches and caged biologically active compounds
and thus must be designed to allow flexible 2-photon based uncaging deep
within tissue with exquisite and user defined precision e.g. at cellular and
subcellular resolution. The system must also be compatible with coordinated
electrophysiological recordings from the preparation undergoing imaging.

The 2-photon microscope system required for these types of experimental
projects, must meet the following criteria: (1) 2-photon microscopy of various
biological preparations ranging from tissue slices to whole animals (mice and
rats) using a broad range of spectral excitation frequencies. (2) 2-photon
uncaging using a similar range of spectral excitation frequencies as a built
in option. (3) Ability to illuminate samples with conventional fluorescent
illumination and visible light and to carry out electrophysiological
recordings from the preparation being used for microscopy. (4) The system
shall have the ability to perform precise user-specified 2-photon uncaging and
should use different galvanometers for scanning and uncaging. (5) The
software controlling the system shall be designed to directly incorporate
electrophysiological recording in parallel to imaging and uncaging. (6) The
company shall supply and build a complete custom system including optical
table and lasers and to coordinate with NIDCR investigators and Project
Officers for the delivery of the complete system. (7) The imaging system must
be capable of fitting within the available imaging room with a 10 foot 6 inch
square floor-plan.

To meet these requirements and in addition to them, the system must include
the following specifications:

1. Automatic switching between two scanning methods:
a. Standard Scanning ? uses X & Y galvanometer driven mirrors
b. High Speed Scanning Option? uses Y galvanometer and Acousto Optic
Deflector (AOD) for X scanning
i. 512 x ~512 pixels at 25 fps
ii. Zoom factors of 1, 2, 3, 4, and 8 times.
2. Systems may be upgraded to the high speed scanning option if it is not
purchased initially.
3. Laser input optics for two simultaneous beams. One for the imaging
optics and the second for uncaging (photolysis) applications. This option is
designed for use with two Ti: Sapphire lasers for simultaneous two-photon
imaging and two-photon uncaging. May be used with a single laser in an
alternating mode between imaging and uncaging.
4. Synchronization of imaging line scans, uncaging, and electrical
recording data in a single computer.
5. A total of six external non-descanned fluorescence detectors may be
used simultaneously:
a. Two or four detectors located above the specimen
b. Two detectors located below the specimen
6. Laser delivery optics utilize a Pockels cell for laser power
attenuation and beam blanking in order to minimize laser pulse dispersion and
the need to pre-chirp the laser in the standard galvanometer based system.
7. Transmitted Dodt gradient contrast detector allows simultaneous
viewing of gradient contrast image and fluorescent images overlaid in the same
or individual image windows.
During acquisition of z series data, the laser power and or the PMT high
voltage can be automatically adjusted as a function of depth into the specimen.

It is anticipated that the construction of such a system will take several
months once the contract is awarded and that the offeror will work closely
with the end users to ensure delivery and installation of the complete system
by June 30, 2008. The imaging system shall be placed within the available
imaging room which cannot exceed a maximum width of 10 feet.

Specific Requirements: The contractor shall be responsible for training,
inside delivering, and installation of the system.

The provisions of FAR Clause 52.212-1, Instructions to Offerors-Commercial
Items (Sept 2006), is applicable to this acquisition.

The provisions of FAR Clause 52.212-2, Evaluation ? Commercial Items (Jan
1999), is applicable to this acquisition. The purchase order award will be
made to the Offeror whose product meets the Government?s minimum performance
specifications, functional specifications, and delivery date as specified
above.

A best buy analysis will be performed taking into consideration price,
shipping points, technical specifications, special features, probable life of
the item selected as compared with that of a comparable item, warranty
considerations, maintenance availability, environmental and energy efficiency
considerations, delivery terms, and past performance. In addition to a price
quote, the Offeror must submit descriptive literature of the product proposed,
a commercial price list, warranty provisions, and any other information the
Offeror considers relevant to the Government?s evaluation of the product
proposed. The Government intends to evaluate the proposals and award the
contract without discussion with Offerors. Therefore, the initial offer
should contain the Offerors best terms for a technical and price standpoint.
However, the Government reserves the right to conduct discussions, request
product samples or demonstrations, if later determined by the Contracting
Officer to be necessary. The Government may reject any and all offers if such
action is deemed necessary. The Government may also waive informalities and
minor irregularities in the offers received.

The provisions of FAR Clause 52.212-3 Offeror Representations and
Certifications ? Commercial Items (Nov 2006), applies to this acquisitions.
The Offeror must include a completed copy of the provision of FAR Clause
52.212-3, Offeror Representations and Certifications ? Commercial Items with
its offer.

The provisions of FAR Clause 52.212-4, Contract Terms and Conditions ?
Commercial Items, applies to this acquisition. The addendum to FAR Clause
5212-4, Contract Terms and Conditions ? Commercial Items is as follows: The
Offeror must include in its quote, the unit price, the list price,
installation charges, shipping and handling cost, the delivery date, prompt
payment discount terms, the F.O.B. point (Destination or Origin), and provided
descriptive literature inclusive of specifications as part of the quotation.
The DUN and Bradstreet Number (DUNs), the Taxpayer Identification Number
(TIN), and the business size. The Offeror must be registered in the
Government?s Central contractor Registry (CCR) System, which is available at
www.ccr.gov.

The FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement
Statutes or Executive Orders ? Commercial Items (June 2007),? Deviation For
Simplified Acquisitions, applies to this acquisition.

The following FAR Clauses cited are applicable to this acquisition: (1)
52.222-26, Equal Opportunity (E.O.) 11246). (2) 52.222-35, Affirmative Action
for Special Disabled and Vietnam Era Veterans (38 U.S.C. 4212). (3) 52.222-
36, Affirmative Action for Handicapped Workers (29 U.S.C. 793). (4) 52,.222-
37, Employment Reports on Special Disabled Veterans and Veterans of the
Vietnam Era (38 U.S.C. 4212). (5) 52.225-3, Buy American Act ? supplies (41
U.S.C. 10). (6) (I) 52.225-21, Buy American Act ? North American Free Trade
Agreement Implementation Act ? Balance of Payments Program (41 U.S.C. 10, Pub.
L. 103-187). (7) (ii) Alternate I of 52.225-21. (8) 52.239-1, Privacy or
Security Safeguards (5 U.S.C. 552a).

There are no numbered notes applicable to this notice.

Quotations are due on Monday September 15, 2007, 10 a.m. Eastern time at the
National heart, Lung and Blood Institute, Office of Acquisitions, Procurement
Branch, 6701 Rockledge Drive, Suite 6042, Bethesda, Maryland 20892-7902.
Attention Cecilia D. Morales, Contract Specialist, (301) 435-0369. Quotations
may be submitted electronically to Moralesc@nhlbi.nih.gov or by FAX to (301)
480-3345. The electronic transmission and fax transmission must referece the
solicitation number: NHLBI-PB(DE)-2007-235/CDM.

All responsible sources may submit a proposal, which if timely received, shall
be considered by the agency.

Company Reports

Get the Dun & Bradstreet Report for Department of Health and Human Services, National