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Tacrolimus Impurities Metabolites

 

View Offers to Sell: Pharmaceuticals - Raw Materials

 

Category: Pharmaceuticals - Pharmaceuticals - Raw Materials

Offer ID: OS1786987 | Offer Post Date: 2012-09-07

TCL01: Tacrolimus Monohydrate [CAS # 109889-09-0]

Tacrolimus (also known as FK-506) is a secondary metabolite isolated


from Streptomyces tsukubaensis. It is a non-polar

macrolide with immunosuppressant activity and originally developed by Fujisawa. Tacrolimus Monohydrate is used as API

for production of its finished dosages including 'Prograf' (0.5 mg, 1 mg, 5 mg per capsule) and 'Protopic' (0.03% & 0.1

% topical ointment).

Physico-Chemical Properties:

Tacrolimus Monohydrate is white or off white crystalline powder, mp 127-129 DC, [a]D23 -84.4 (c = 1.02 in chloroform);

Soluble in methanol, ethanol, acetone, ethyl acetate, diethyl ether, chloroform; Slightly soluble in petroleum ether,

hexane; Not soluble in water.

TCL02: Ascomycin; Immunomycin; FK-520; FR-900520

[CAS # 104987-12-4]

TCL03: Dihydro Tacrolimus; Dihydro FK-506; Tsukubamycin B

[CAS # 104987-30-6]

Tacrolimus Impurities Metabolites

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Company Information

Company Name: Molcan Corporation
Address: #39, 70 East Beaver Creek Road
City: Richmond Hill
State/Province: ON
Country: Canada
Phone: 19057315537
Fax: 1-905-248-3843
Contact: Teresa Poon
Email: Email
Showroom: View this company's showroom
Website: http://www.molcan.com
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Mycophenolate Impurities Metabolites (2012-09-07 - Pharmaceuticals - Raw Materials) by Molcan Corporation from Canada: MCP01: Mycophenolate Mofetil [ CAS # 128794-94-5 ] MCP02: O-Desmethyl Mycophenolate Mofetil ( EP Impurity A = USP Related Compound A ) 2-Morpholinoethyl-(E)-6-(1,3-dihydro-4,6-dihydroxy-7-methyl-3 -

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